Tan Lab | DSigDB

Gene Set: D4 : CTD - Terazosin

Collection

D4 : CTD

Chemical Name

Terazosin ( From PubChem : TERAZOSIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
387.433 g/mol	1	9	1.6409	True

Structure

InChI

InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)/t14-/m0/s1

InChIKey

VCKUSRYTPJJLNI-AWEZNQCLSA-N

Links

Gene (13 / 17)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			ADRA1A		C041226
CTD	affects(binding)			ADRA1B		C041226
CTD	affects(binding)			ADRA1D		C041226
CTD	increases(expression)			BAX		C041226
CTD	decreases(expression)			BCL2		C041226
CTD	increases(expression)			CDKN1B		C041226
PubChem	Potency	uM	4.467	HTT	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-		CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	4466.800	HTT	-	Target : CHEMBL5514

Download gene sets

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