Tan Lab | DSigDB

Gene Set: D4 : CTD - tetrachlorodian

Collection

D4 : CTD

Chemical Name

tetrachlorodian ( From PubChem : TETRACHLORODIAN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
366.067 g/mol	2	2	6.0373	False(3/4)

Structure

InChI

InChI=1S/C15H12Cl4O2/c1-15(2,7-3-9(16)13(20)10(17)4-7)8-5-11(18)14(21)12(19)6-8/h3-6,20-21H,1-2H3

InChIKey

KYPYTERUKNKOLP-UHFFFAOYSA-N

Links

Gene (15 / 47)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			AR		C041181
CTD	decreases(reaction)			AR		C041181
CTD	affects(binding)			AR		C041181
CTD	affects(binding)			ESR1		C041181
CTD	increases(activity)			ESR1		C041181
CTD	affects(binding)			ESR1		C041181
CTD	increases(activity)			ESR1		C041181
CTD	affects(binding)			ESR2		C041181
CTD	increases(activity)			ESR2		C041181
CTD	increases(activity)			ESR2		C041181
CTD	affects(binding)			NR1I2		C041181
CTD	increases(activity)			NR1I2		C041181
CTD	increases(expression)			PGR		C041181
CTD	affects(binding)			PPARG		C041181
CTD	increases(activity)			PPARG		C041181
CTD	affects(binding)			PPARG		C041181
CTD	increases(activity)			PPARG		C041181
CTD	increases(activity)			PPARG		C041181
CTD	affects(binding)			SERPINA7		C041181
CTD	decreases(reaction)			SERPINA7		C041181
CTD	increases(expression)			TFF1		C041181
CTD	decreases(reaction)			THRA		C041181
CTD	increases(activity)			THRA		C041181
CTD	decreases(reaction)			THRB		C041181
CTD	increases(activity)			THRB		C041181
CTD	affects(binding)			TTR		C041181
CTD	affects(binding)			TTR		C041181
CTD	decreases(reaction)			TTR		C041181
PubChem	Potency-Replicate_1	uM	3.438	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	12.784	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	13.801	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	17.229	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	21.872	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	27.536	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	51.880	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	54.975	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	50.882	HSPB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		HSPB1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	15.355	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	16.580	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	19.331	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	19.331	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	6.917	NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	12.307	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :

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