Tan Lab | DSigDB

Gene Set: D4 : CTD - caffeic acid

Collection

D4 : CTD

Chemical Name

caffeic acid ( From PubChem : CAFFEIC ACID )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
180.157 g/mol	3	4	1.1956	True

Structure

InChI

InChI=1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2+

InChIKey

QAIPRVGONGVQAS-DUXPYHPUSA-N

Links

Gene (62 / 115)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			ALOX15		C040048
CTD	increases(activity)			ALOX15		C040048
CTD	decreases(activity)			ALOX15		C040048
CTD	decreases(activity)			ALOX15		C040048
CTD	decreases(reaction)			ALOX15		C040048
CTD	increases(activity)			ALOX15		C040048
CTD	decreases(chemical synthesis)			ALOX15		C040048
CTD	increases(abundance)			ALOX15		C040048
CTD	decreases(expression)			ATP6V0D2		C040048
CTD	increases(reaction)			ATP6V0D2		C040048
CTD	decreases(activity)			CASP3		C040048
CTD	decreases(reaction)			CASP3		C040048
CTD	increases(activity)			CASP3		C040048
CTD	affects(cotreatment)			CDC20		C040048
CTD	increases(expression)			CDC20		C040048
CTD	increases(expression)			CDK2		C040048
CTD	increases(reaction)			CDK2		C040048
CTD	increases(methylation)			COMT		C040048
CTD	decreases(expression)			CTF1		C040048
CTD	increases(reaction)			CTF1		C040048
CTD	decreases(expression)			CXCL2		C040048
CTD	increases(reaction)			CXCL2		C040048
CTD	decreases(reaction)			CXCL8		C040048
CTD	increases(expression)			CXCL8		C040048
CTD	decreases(expression)			DAP		C040048
CTD	increases(reaction)			DAP		C040048
CTD	decreases(expression)			DNAJB11		C040048
CTD	increases(reaction)			DNAJB11		C040048
CTD	increases(expression)			DPYSL4		C040048
CTD	increases(reaction)			DPYSL4		C040048
CTD	decreases(expression)			ELMO2		C040048
CTD	increases(reaction)			ELMO2		C040048
CTD	increases(expression)			ERF		C040048
CTD	increases(reaction)			ERF		C040048
CTD	decreases(expression)			FLRT2		C040048
CTD	increases(reaction)			FLRT2		C040048
CTD	decreases(expression)			FLT4		C040048
CTD	increases(reaction)			FLT4		C040048
CTD	decreases(expression)			GSR		C040048
CTD	increases(reaction)			GSR		C040048
CTD	decreases(expression)			HSP90B1		C040048
CTD	increases(reaction)			HSP90B1		C040048
CTD	increases(expression)			HSPE1		C040048
CTD	increases(reaction)			HSPE1		C040048
CTD	decreases(expression)			IL21R		C040048
CTD	increases(reaction)			IL21R		C040048
CTD	affects(cotreatment)			KIF15		C040048
CTD	increases(expression)			KIF15		C040048
CTD	increases(expression)			KIF20B		C040048
CTD	increases(reaction)			KIF20B		C040048
CTD	decreases(reaction)			KIF2C		C040048
CTD	increases(expression)			KIF2C		C040048
CTD	affects(cotreatment)			MAP2K5		C040048
CTD	decreases(expression)			MAP2K5		C040048
CTD	decreases(expression)			MFN1		C040048
CTD	increases(reaction)			MFN1		C040048
CTD	decreases(activity)			MPO		C040048
CTD	decreases(expression)			MRPL45		C040048
CTD	increases(reaction)			MRPL45		C040048
CTD	decreases(expression)			MRRF		C040048
CTD	increases(reaction)			MRRF		C040048
CTD	increases(expression)			NDP		C040048
CTD	increases(expression)			NOS3		C040048
CTD	decreases(expression)			PDCD10		C040048
CTD	increases(reaction)			PDCD10		C040048
CTD	affects(cotreatment)			PLK1		C040048
CTD	increases(expression)			PLK1		C040048
CTD	increases(expression)			PLK4		C040048
CTD	increases(reaction)			PLK4		C040048
CTD	decreases(expression)			PRDX5		C040048
CTD	increases(reaction)			PRDX5		C040048
CTD	decreases(expression)			PTGS2		C040048
CTD	increases(reaction)			PTGS2		C040048
CTD	decreases(expression)			PTX3		C040048
CTD	increases(reaction)			PTX3		C040048
CTD	decreases(expression)			SFXN4		C040048
CTD	increases(reaction)			SFXN4		C040048
CTD	affects(binding)			SNCA		C040048
CTD	decreases(reaction)			SNCA		C040048
CTD	affects(cotreatment)			STK32A		C040048
CTD	decreases(expression)			STK32A		C040048
CTD	increases(sulfation)			SULT1A1		C040048
CTD	increases(sulfation)			SULT1A2		C040048
CTD	increases(sulfation)			SULT1A3		C040048
CTD	increases(sulfation)			SULT1C2		C040048
CTD	affects(expression)			TP53		C040048
CTD	decreases(expression)			TP53		C040048
CTD	increases(reaction)			TP53		C040048
CTD	increases(oxidation)			TYR		C040048
CTD	decreases(abundance)			TYR		C040048
CTD	increases(expression)			UBE2C		C040048
CTD	increases(reaction)			UBE2C		C040048
CTD	increases(glucuronidation)			UGT1A10		C040048
CTD	increases(glucuronidation)			UGT1A3		C040048
CTD	increases(glucuronidation)			UGT1A7		C040048
CTD	increases(glucuronidation)			UGT1A8		C040048
PubChem	None	uM		ALPL	-	GI(Protien) :
PubChem	Potency	uM	3.162	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	10.621	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	11.220	EHMT2	-	GI(Protien) :
PubChem	None	uM		ESR2	-	GI(Protien) :
PubChem	Potency	uM	7.943	GAA	-	GI(Protien) :
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	None	uM		GFER	-	GI(Protien) :
PubChem	Potency	uM	1.995	GLS	-	GI(Protien) :
PubChem	None	uM		HSP90AA1	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	IC50	uM		MPI	-	GI(Protien) :
ChEMBL	Potency	nM	3162.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	11220.200	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	10621.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	7943.300	GAA	-	Target : CHEMBL2608
ChEMBL	Potency	nM	1995.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	15848.900	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	562.300	KDM4E	-	Target : CHEMBL1293226

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