Tan Lab | DSigDB

Gene Set: D4 : CTD - myricetin

Collection

D4 : CTD

Chemical Name

myricetin ( From PubChem : MYRICETIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
318.235 g/mol	6	8	1.6936	False(3/4)

Structure

InChI

InChI=1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H

InChIKey

IKMDFBPHZNJCSN-UHFFFAOYSA-N

Links

Gene (100 / 233)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(export)			ABCC1		C040015
CTD	decreases(reaction)			ABCC1		C040015
CTD	decreases(response to substance)			ABCC1		C040015
CTD	decreases(activity)			ABCC1		C040015
CTD	affects(export)			ABCC2		C040015
CTD	decreases(reaction)			ABCC2		C040015
CTD	decreases(response to substance)			ABCC2		C040015
CTD	decreases(activity)			ABCC2		C040015
CTD	increases(cleavage)			ARHGDIB		C040015
CTD	decreases(expression)			BAX		C040015
CTD	decreases(reaction)			BAX		C040015
CTD	decreases(expression)			BCL2		C040015
CTD	decreases(reaction)			BCL2		C040015
CTD	increases(activity)			CASP3		C040015
CTD	increases(cleavage)			CASP3		C040015
CTD	increases(activity)			CASP9		C040015
CTD	decreases(reaction)			CAT		C040015
CTD	increases(activity)			CAT		C040015
CTD	decreases(expression)			CCNB1		C040015
CTD	increases(expression)			CDKN1A		C040015
CTD	increases(expression)			CDKN2C		C040015
CTD	affects(cotreatment)			COMT		C040015
CTD	decreases(activity)			COMT		C040015
CTD	decreases(expression)			CTNNB1		C040015
CTD	increases(activity)			CTNNB1		C040015
CTD	affects(localization)			CYCS		C040015
CTD	decreases(reaction)			CYCS		C040015
CTD	decreases(activity)			CYP1A1		C040015
CTD	decreases(activity)			CYP1B1		C040015
CTD	affects(cotreatment)			DNMT1		C040015
CTD	decreases(activity)			DNMT1		C040015
CTD	decreases(expression)			EGLN1		C040015
CTD	increases(activity)			EGLN1		C040015
CTD	decreases(expression)			FBP1		C040015
CTD	decreases(reaction)			HGF		C040015
CTD	increases(phosphorylation)			HGF		C040015
CTD	increases(activity)			HIF1A		C040015
CTD	increases(expression)			HIF1A		C040015
CTD	increases(expression)			HMOX1		C040015
CTD	affects(cotreatment)			IL6		C040015
CTD	decreases(reaction)			IL6		C040015
CTD	increases(secretion)			IL6		C040015
CTD	decreases(reaction)			MET		C040015
CTD	increases(phosphorylation)			MET		C040015
CTD	decreases(reaction)			MMP9		C040015
CTD	increases(activity)			MMP9		C040015
CTD	decreases(expression)			MYC		C040015
CTD	increases(activity)			MYC		C040015
CTD	increases(expression)			NFE2L2		C040015
CTD	decreases(activity)			PARG		C040015
CTD	decreases(activity)			PARP1		C040015
CTD	increases(cleavage)			PARP1		C040015
CTD	decreases(expression)			PSCA		C040015
CTD	decreases(reaction)			PTGS2		C040015
CTD	increases(expression)			PTGS2		C040015
CTD	affects(cotreatment)			RELA		C040015
CTD	affects(localization)			RELA		C040015
CTD	decreases(reaction)			RELA		C040015
CTD	increases(activity)			RELA		C040015
CTD	increases(activity)			SIRT1		C040015
CTD	decreases(expression)			SIRT1		C040015
CTD	increases(expression)			SIRT1		C040015
CTD	affects(transport)			SLC2A1		C040015
CTD	decreases(reaction)			SLC2A1		C040015
CTD	decreases(activity)			SLC2A1		C040015
CTD	affects(cotreatment)			TNF		C040015
CTD	decreases(reaction)			TNF		C040015
CTD	increases(secretion)			TNF		C040015
CTD	decreases(activity)			TOP2A		C040015
CTD	increases(expression)			TP53I3		C040015
CTD	increases(expression)			TP63		C040015
CTD	increases(expression)			TP73		C040015
PubChem	None	uM		ABL1	-	GI(Protien) :
PubChem	Potency	uM	3.548	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	8.912	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	12.589	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	1.585	ALOX15	-	GI(Protien) :
PubChem	Potency	uM	2.512	ALOX15	-	GI(Protien) :
PubChem	IC50_Mean	uM	33.200	ALPL	-	GI(Protien) :
PubChem	EC50_Mean	uM	32.300	ALPPL2	-	GI(Protien) :
PubChem	IC50_Mean	uM	17.500	APOBEC3A	-	GI(Protien) :
PubChem	IC50_Mean	uM	2.390	APOBEC3G	-	GI(Protien) :
PubChem	None	uM		APOBEC3G	-	GI(Protien) :
PubChem	None	uM		APOBEC3G	-	GI(Protien) :
PubChem	Potency	uM	22.387	BAZ2B	-	GI(Protien) :
PubChem	Potency	uM	14.125	BLM	-	GI(Protien) :
PubChem	Potency	uM	14.125	BLM	-	GI(Protien) :
PubChem	AC50_uM	uM	0.461	CASP6	-	GI(Protien) :
PubChem	None	uM		CASP6	-	GI(Protien) :
PubChem	Potency	uM	14.125	CBX1	-	GI(Protien) :
PubChem	None	uM		CLK3	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	10.000	CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	10.000	CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	12.589	CYP2C9	-	GI(Protien) :
PubChem	None	uM		CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	0.562	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	1.683	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	1.995	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	2.818	EHMT2	-	GI(Protien) :
PubChem	None	uM		ESR1	-	GI(Protien) :
PubChem	None	uM		EZH2	-	GI(Protien) :
PubChem	Potency	uM	1.000	FEN1	-	GI(Protien) :
PubChem	Potency	uM	1.413	FEN1	-	GI(Protien) :
PubChem	Potency	uM	1.500	FEN1	-	GI(Protien) :
PubChem	Potency	uM	1.500	FEN1	-	GI(Protien) :
PubChem	Potency	uM	2.239	FEN1	-	GI(Protien) :
PubChem	Potency	uM	2.686	FEN1	-	GI(Protien) :
PubChem	AbsAC1_uM	uM	4.370	FGF22	-	GI(Protien) :
PubChem	None	uM		FGF22	-	GI(Protien) :
PubChem	None	uM		GFER	-	GI(Protien) :
PubChem	Potency	uM	3.981	GLS	-	GI(Protien) :
PubChem	AC50_uM	uM	4.133	GSK3A	-	GI(Protien) :
PubChem	None	uM		GSK3A	-	GI(Protien) :
PubChem	None	uM		GSTO1	-	GI(Protien) :
PubChem	None	uM		GSTO1	-	GI(Protien) :
PubChem	Potency	uM	7.943	HPGD	-	GI(Protien) :
PubChem	Potency	uM	10.000	HPGD	-	GI(Protien) :
PubChem	Potency	uM	12.589	HPGD	-	GI(Protien) :
PubChem	None	uM		HSP90AA1	-	GI(Protien) :
PubChem	None	uM		ITGA4	-	GI(Protien) :
PubChem	Potency	uM	0.150	L3MBTL1	-	GI(Protien) :
PubChem	Potency	uM	0.447	L3MBTL1	-	GI(Protien) :
PubChem	Potency	uM	7.080	MAPT	-	GI(Protien) :
PubChem	Potency	uM	10.000	MAPT	-	GI(Protien) :
PubChem	None	uM		MBD2	-	GI(Protien) :
PubChem	Potency	uM	6.310	MPHOSPH8	-	GI(Protien) :
PubChem	Potency	uM	8.437	MPHOSPH8	-	GI(Protien) :
PubChem	None	uM		PAFAH1B2	-	GI(Protien) :
PubChem	None	uM		PAFAH1B3	-	GI(Protien) :
PubChem	None	uM		PIM2	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
PubChem	Potency	uM	9.466	PLK1	-	GI(Protien) :
PubChem	Potency	uM	0.200	POLB	-	GI(Protien) :
PubChem	Potency	uM	0.708	POLH	-	GI(Protien) :
PubChem	Potency	uM	1.259	POLH	-	GI(Protien) :
PubChem	Potency	uM	1.694	POLH	-	GI(Protien) :
PubChem	Potency	uM	0.398	POLI	-	GI(Protien) :
PubChem	Potency	uM	1.062	POLI	-	GI(Protien) :
PubChem	Potency	uM	1.122	POLI	-	GI(Protien) :
PubChem	Potency	uM	3.162	POLI	-	GI(Protien) :
PubChem	Potency	uM	0.150	POLK	-	GI(Protien) :
PubChem	Potency	uM	0.282	POLK	-	GI(Protien) :
PubChem	Potency	uM	0.299	POLK	-	GI(Protien) :
PubChem	Potency	uM	0.844	POLK		GI(Protien) :
PubChem	Potency	uM	0.947	POLK	-	GI(Protien) :
PubChem	Potency	uM	1.122	POLK	-	GI(Protien) :
PubChem	Potency	uM	1.995	POLK	-	GI(Protien) :
PubChem	Potency	uM	2.239	POLK	-	GI(Protien) :
PubChem	Potency	uM	2.818	POLK	-	GI(Protien) :
PubChem	None	uM		PREPL	-	GI(Protien) :
PubChem	None	uM		PREPL	-	GI(Protien) :
PubChem	None	uM		PRMT1	-	GI(Protien) :
PubChem	IC50	uM	0.758	PSIP1	-	GI(Protien) :
PubChem	IC50	uM	1.140	PSIP1	-	GI(Protien) :
PubChem	None	uM		PSIP1	-	GI(Protien) :
PubChem	None	uM		PSIP1	-	GI(Protien) :
PubChem	None	uM		PSIP1	-	GI(Protien) :
PubChem	None	uM		RIN1	-	GI(Protien) :
PubChem	None	uM		RNASEH1	-	GI(Protien) :
PubChem	None	uM		SENP1	-	GI(Protien) :
PubChem	None	uM		SENP8	-	GI(Protien) :
PubChem	EC50_uM	uM	17.970	STK33	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	Potency	uM	11.220	TDP1	-	GI(Protien) :
PubChem	Potency	uM	18.356	TDP1	-	GI(Protien) :
PubChem	Potency	uM	10.000	THPO	-	GI(Protien) :
PubChem	None	uM		TRA	-	GI(Protien) :
PubChem	None	uM		TRA	-	GI(Protien) :
PubChem	None	uM		UHRF1	-	GI(Protien) :
PubChem	Potency	uM	1.122	WRN	-	GI(Protien) :
ChEMBL	Potency	nM	8912.500	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	3548.100	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	12589.300	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	1584.900	ALOX15	-	Target : CHEMBL2903
ChEMBL	Potency	nM	2511.900	ALOX15	-	Target : CHEMBL2903
ChEMBL	IC50	nM	33200.000	ALPL	-	Target : CHEMBL5979
ChEMBL	EC50	nM	32300.000	ALPPL2	-	Target : CHEMBL3402
ChEMBL	Potency	nM	7079.500	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	354.800	APEX1	-	Target : CHEMBL5619
ChEMBL	IC50	nM	17500.000	APOBEC3A	-	Target : CHEMBL1741179
ChEMBL	IC50	nM	2390.000	APOBEC3G	-	Target : CHEMBL1741217
ChEMBL	Potency	nM	22387.200	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Potency	nM	14125.400	BLM	-	Target : CHEMBL1293237
ChEMBL	Potency	nM	14125.400	BLM	-	Target : CHEMBL1293237
ChEMBL	Potency	nM	14125.400	CBX1	-	Target : CHEMBL1741193
ChEMBL	AC50	nM	5011.870	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	1995.260	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	10000.000	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	10000.000	CYP2C9	-	Target : CHEMBL3397
ChEMBL	AC50	nM	12589.200	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	10000.000	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	12589.300	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	1683.400	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	562.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	1995.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	2818.400	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	1500.300	FEN1	-	Target : CHEMBL5027
ChEMBL	Activity	-		GPR35	-	Target : CHEMBL1293267
ChEMBL	Potency	nM	10000.000	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	7943.300	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	12589.300	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	7943.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	199.500	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	158.500	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	125.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	3548.100	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	2511.900	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	7079.500	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	4466.800	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	446.700	L3MBTL1	-	Target : CHEMBL1287622
ChEMBL	Potency	nM	7079.500	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	7079.500	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	10000.000	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	10000.000	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	6309.600	MPHOSPH8	-	Target : CHEMBL1741210
ChEMBL	Potency	nM	8436.800	MPHOSPH8	-	Target : CHEMBL1741210
ChEMBL	Inhibition	-		PIK3CA	-	Target : CHEMBL4005
ChEMBL	Inhibition	-		PIK3CA	-	Target : CHEMBL4005
ChEMBL	Potency	nM	199.500	POLB	-	Target : CHEMBL2392
ChEMBL	Potency	nM	891.300	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	1412.500	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	891.300	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	4466.800	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	3162.300	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	10000.000	THPO	-	Target : CHEMBL1293256
ChEMBL	Activity	-		TOP1	-	Target : CHEMBL1781
ChEMBL	Activity	-		TOP2A	-	Target : CHEMBL1806
ChEMBL	Activity	-		TOP2A	-	Target : CHEMBL1806
ChEMBL	Activity	-		TOP2A	-	Target : CHEMBL1806

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