Tan Lab | DSigDB

Gene Set: D4 : CTD - cryptotanshinone

Collection

D4 : CTD

Chemical Name

cryptotanshinone ( From PubChem : CRYPTOTANSHINONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
296.36 g/mol	0	3	3.4433	True

Structure

InChI

InChI=1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1

InChIKey

GVKKJJOMQCNPGB-JTQLQIEISA-N

Links

Gene (31 / 49)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			ACHE		C037886
CTD	decreases(activity)			ACHE		C037886
CTD	increases(expression)			AHR		C037886
CTD	increases(reaction)			AHR		C037886
CTD	affects(binding)			BCHE		C037886
CTD	decreases(activity)			BCHE		C037886
CTD	increases(expression)			CYP1A1		C037886
CTD	increases(reaction)			CYP1A1		C037886
CTD	decreases(reaction)			CYP1A1		C037886
CTD	increases(expression)			CYP1A2		C037886
CTD	increases(reaction)			CYP1A2		C037886
CTD	decreases(reaction)			CYP1A2		C037886
CTD	increases(expression)			CYP3A4		C037886
CTD	increases(activity)			NR1I2		C037886
PubChem	Potency	uM	12.589	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	14.125	BAZ2B	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	Potency	uM	18.356	GMNN	-	GI(Protien) :
PubChem	None	uM		GSTO1	-	GI(Protien) :
PubChem	None	uM		KCNK3	-	GI(Protien) :
PubChem	None	uM		LYPLA2	-	GI(Protien) :
PubChem	Potency	uM	12.589	MAPT	-	GI(Protien) :
PubChem	None	uM		MITF	-	GI(Protien) :
PubChem	None	uM		PAFAH1B3	-	GI(Protien) :
PubChem	None	uM		PAFAH2	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
PubChem	Potency	uM	26.680	PLK1	-	GI(Protien) :
PubChem	Potency	uM	22.387	POLB	-	GI(Protien) :
PubChem	Potency	uM	35.481	POLH	-	GI(Protien) :
PubChem	Potency	uM	22.387	POLI	-	GI(Protien) :
PubChem	Potency	uM	4.467	SMAD3	-	GI(Protien) :
PubChem	None	uM		STAT1	-	GI(Protien) :
PubChem	Potency	uM	5.173	TDP1	-	GI(Protien) :
PubChem	Potency	uM	5.173	TDP1	-	GI(Protien) :
PubChem	None	uM		UCHL5	-	GI(Protien) :
PubChem	None	uM		UCHL5	-	GI(Protien) :
PubChem	Potency	uM	31.623	USP1	-	GI(Protien) :
PubChem	Potency	uM	11.220	VDR	-	GI(Protien) :
PubChem	Potency	uM	19.953	VDR	-	GI(Protien) :
PubChem	Potency	uM	25.119	VDR	-	GI(Protien) :
PubChem	Potency	uM	28.184	VDR	-	GI(Protien) :
PubChem	Potency	uM	28.184	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	14125.400	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Potency	nM	31622.800	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	12589.300	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	22387.200	POLB	-	Target : CHEMBL2392
ChEMBL	Inhibition	-		PTPN11	-	Target : CHEMBL3864

Download gene sets

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