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Gene Set: D4 : CTD - galangin

Collection D4 : CTD
Chemical Name galangin ( From PubChem : GALANGIN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotApprovedNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
270.237 g/mol 3 5 2.5768 True
Structure
InChI InChI=1S/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H
InChIKey VCCRNZQBSJXYJD-UHFFFAOYSA-N
Links

Gene (27 / 64)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(activity)ABCC1
C037032
CTDaffects(cotreatment)CASP1
C037032
CTDdecreases(reaction)CASP1
C037032
CTDincreases(activity)CASP1
C037032
CTDaffects(cotreatment)CXCL8
C037032
CTDdecreases(reaction)CXCL8
C037032
CTDincreases(expression)CXCL8
C037032
CTDdecreases(reaction)CYP1A1
C037032
CTDincreases(expression)CYP1A1
C037032
CTDdecreases(activity)CYP1A1
C037032
CTDdecreases(reaction)CYP1A2
C037032
CTDincreases(expression)CYP1A2
C037032
CTDdecreases(activity)CYP1A2
C037032
CTDaffects(binding)CYP1B1
C037032
CTDdecreases(activity)CYP1B1
C037032
CTDdecreases(reaction)CYP2C9
C037032
CTDincreases(hydroxylation)CYP2C9
C037032
CTDdecreases(reaction)CYP3A4
C037032
CTDincreases(chemical synthesis)CYP3A4
C037032
CTDincreases(oxidation)CYP3A4
C037032
CTDincreases(reaction)CYP3A4
C037032
CTDdecreases(activity)CYP3A4
C037032
CTDdecreases(reaction)EPAS1
C037032
CTDincreases(expression)EPAS1
C037032
CTDdecreases(activity)GSTP1
C037032
CTDdecreases(reaction)HIF1A
C037032
CTDincreases(expression)HIF1A
C037032
CTDaffects(cotreatment)IL1B
C037032
CTDdecreases(reaction)IL1B
C037032
CTDincreases(expression)IL1B
C037032
CTDaffects(cotreatment)IL6
C037032
CTDdecreases(reaction)IL6
C037032
CTDincreases(expression)IL6
C037032
CTDaffects(cotreatment)NFKBIA
C037032
CTDdecreases(reaction)NFKBIA
C037032
CTDincreases(degradation)NFKBIA
C037032
CTDaffects(cotreatment)RELA
C037032
CTDaffects(localization)RELA
C037032
CTDdecreases(reaction)RELA
C037032
CTDaffects(cotreatment)TNF
C037032
CTDdecreases(reaction)TNF
C037032
CTDincreases(expression)TNF
C037032
CTDincreases(glucuronidation)UGT1A1
C037032
CTDincreases(glucuronidation)UGT1A10
C037032
CTDincreases(glucuronidation)UGT1A7
C037032
CTDincreases(glucuronidation)UGT1A8
C037032
CTDincreases(glucuronidation)UGT1A9
C037032
CTDincreases(metabolic processing)UGT2B15
C037032
PubChem PotencyuM12.990ATAD5-GI(Protien) :
PubChem IC50_CF-PAF_MeanuM3.270CFTR-GI(Protien) :
PubChem NoneuMCFTR-GI(Protien) :
PubChem NoneuMCFTR-GI(Protien) :
PubChem IC50_CF-PAF_MeanuMCFTR-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM3.981CYP2C19-GI(Protien) :
PubChem PotencyuM3.162CYP2C9-GI(Protien) :
PubChem PotencyuM19.953CYP2D6-GI(Protien) :
PubChem PotencyuM15.849CYP3A4-GI(Protien) :
PubChem PotencyuM29.855TDP1-GI(Protien) :
ChEMBLPotencynM12990.000ATAD5
-Target : CHEMBL1741209
ChEMBLPotencynM3981.100CYP2C19
-Target : CHEMBL3622
ChEMBLPotencynM3162.300CYP2C9
-Target : CHEMBL3397
ChEMBLPotencynM19952.600CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM15848.900CYP3A4
-Target : CHEMBL340
Download gene sets gmt, text, Detailed text
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Aurora, CO 80045, USA

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