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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline

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Collection	D4 : CTD
Chemical Name	2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline ( From PubChem : MEIQX )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 213.239 g/mol 1 5 1.9883 True
Structure
InChI	InChI=1S/C11H11N5/c1-6-5-13-7-3-4-8-10(9(7)14-6)15-11(12)16(8)2/h3-5H,1-2H3,(H2,12,15)
InChIKey	DVCCCQNKIYNAKB-UHFFFAOYSA-N
Links
Gene (136 / 175) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(expression) ABCC9 C036990 CTD increases(expression) ABCD3 C036990 CTD decreases(expression) ACSS1 C036990 CTD increases(expression) ADORA2B C036990 CTD decreases(expression) ADSS C036990 CTD decreases(reaction) AHR C036990 CTD increases(expression) AHR C036990 CTD increases(expression) ALDH3A1 C036990 CTD increases(expression) ANLN C036990 CTD increases(expression) APAF1 C036990 CTD decreases(expression) ARG1 C036990 CTD affects(response to substance) ARNT C036990 CTD increases(expression) ASAP1 C036990 CTD increases(expression) ATP11B C036990 CTD decreases(expression) BAX C036990 CTD increases(expression) BCL2 C036990 CTD decreases(expression) C1QTNF7 C036990 CTD decreases(expression) CACNA1D C036990 CTD increases(expression) CASC5 C036990 CTD affects(cotreatment) CASP3 C036990 CTD increases(activity) CASP3 C036990 CTD decreases(expression) CASP8 C036990 CTD decreases(expression) CCDC47 C036990 CTD increases(expression) CDC25C C036990 CTD increases(expression) CDK1 C036990 CTD increases(expression) CDK13 C036990 CTD increases(expression) CDKN1A C036990 CTD increases(phosphorylation) CEBPB C036990 CTD affects(response to substance) CEBPB C036990 CTD increases(expression) CEP55 C036990 CTD increases(expression) CFAP45 C036990 CTD decreases(expression) CFHR4 C036990 CTD decreases(expression) CLDN14 C036990 CTD decreases(expression) CLYBL C036990 CTD increases(expression) COL9A2 C036990 CTD decreases(expression) CSGALNACT1 C036990 CTD affects(cotreatment) CYP1A1 C036990 CTD increases(expression) CYP1A1 C036990 CTD increases(expression) CYP1A1 C036990 CTD decreases(reaction) CYP1A1 C036990 CTD increases(expression) CYP1A1 C036990 CTD affects(activity) CYP1A1 C036990 CTD affects(cotreatment) CYP1A2 C036990 CTD increases(expression) CYP1A2 C036990 CTD increases(activity) CYP1A2 C036990 CTD increases(expression) CYP1A2 C036990 CTD decreases(reaction) CYP1A2 C036990 CTD increases(expression) CYP1A2 C036990 CTD affects(metabolic processing) CYP1A2 C036990 CTD affects(cotreatment) CYP1A2 C036990 CTD increases(response to substance) CYP1A2 C036990 CTD decreases(activity) CYP1A2 C036990 CTD increases(activity) CYP1A2 C036990 CTD increases(hydroxylation) CYP1A2 C036990 CTD increases(chemical synthesis) CYP1A2 C036990 CTD increases(metabolic processing) CYP1A2 C036990 CTD increases(oxidation) CYP1A2 C036990 CTD increases(activity) CYP1A2 C036990 CTD increases(oxidation) CYP1A2 C036990 CTD decreases(reaction) CYP1A2 C036990 CTD increases(expression) CYP1A2 C036990 CTD affects(cotreatment) CYP1B1 C036990 CTD increases(expression) CYP1B1 C036990 CTD increases(expression) CYP1B1 C036990 CTD affects(response to substance) CYP1B1 C036990 CTD decreases(expression) CYP2C8 C036990 CTD affects(cotreatment) CYP3A7 C036990 CTD increases(response to substance) CYP3A7 C036990 CTD decreases(expression) CYTB C036990 CTD increases(expression) DAPL1 C036990 CTD increases(expression) DDX42 C036990 CTD decreases(expression) DHRS2 C036990 CTD increases(expression) DIAPH3 C036990 CTD decreases(expression) DMXL2 C036990 CTD increases(expression) DUOX2 C036990 CTD increases(expression) DUSP16 C036990 CTD increases(expression) E2F7 C036990 CTD decreases(expression) EGR1 C036990 CTD affects(response to substance) EPS8L3 C036990 CTD decreases(expression) ERCC1 C036990 CTD increases(expression) ERCC6L C036990 CTD increases(expression) ESCO2 C036990 CTD decreases(reaction) ESR1 C036990 CTD increases(activity) ESR1 C036990 CTD decreases(activity) ESR1 C036990 CTD decreases(expression) FAM153A C036990 CTD decreases(expression) FHIT C036990 CTD decreases(expression) FOS C036990 CTD decreases(expression) FSD1 C036990 CTD increases(expression) GABPB1 C036990 CTD increases(expression) GADD45A C036990 CTD increases(expression) GJC3 C036990 CTD decreases(expression) GNAT1 C036990 CTD decreases(expression) GNMT C036990 CTD increases(expression) GPATCH1 C036990 CTD decreases(expression) GSTA1 C036990 CTD affects(response to substance) GSTM1 C036990 CTD affects(response to substance) GSTP1 C036990 CTD affects(response to substance) GSTT1 C036990 CTD decreases(expression) H6PD C036990 CTD decreases(expression) HIPK3 C036990 CTD affects(cotreatment) HMOX1 C036990 CTD increases(expression) HMOX1 C036990 CTD increases(expression) IL3RA C036990 CTD decreases(expression) IMPG2 C036990 CTD increases(expression) INCENP C036990 CTD increases(expression) INPP5D C036990 CTD increases(expression) KCNV1 C036990 CTD increases(expression) KCTD2 C036990 CTD increases(expression) KIF1B C036990 CTD decreases(expression) KIFC1 C036990 CTD increases(expression) KLF1 C036990 CTD decreases(expression) KLF6 C036990 CTD increases(expression) LAMA1 C036990 CTD decreases(expression) LIF C036990 CTD increases(expression) LRRC58 C036990 CTD increases(expression) MAT2A C036990 CTD increases(expression) MKI67 C036990 CTD affects(cotreatment) NAT2 C036990 CTD increases(response to substance) NAT2 C036990 CTD affects(cotreatment) NAT2 C036990 CTD increases(expression) NAT2 C036990 CTD increases(expression) NEK2 C036990 CTD affects(cotreatment) NFE2L2 C036990 CTD increases(expression) NFE2L2 C036990 CTD increases(expression) NMU C036990 CTD decreases(expression) NR0B2 C036990 CTD affects(cotreatment) OAT C036990 CTD increases(response to substance) OAT C036990 CTD increases(expression) ORC1 C036990 CTD decreases(expression) PDZD7 C036990 CTD decreases(expression) PGM5 C036990 CTD decreases(expression) PIM2 C036990 CTD decreases(expression) PIP5KL1 C036990 CTD affects(cotreatment) POR C036990 CTD increases(response to substance) POR C036990 CTD increases(expression) POTED C036990 CTD decreases(expression) PRSS21 C036990 CTD increases(metabolic processing) PTGS1 C036990 CTD increases(metabolic processing) PTGS2 C036990 CTD increases(expression) RAB7B C036990 CTD decreases(expression) RAD23B C036990 CTD increases(expression) RAD51AP1 C036990 CTD increases(expression) RAD54L C036990 CTD decreases(expression) RAPGEF1 C036990 CTD decreases(expression) RBBP6 C036990 CTD increases(expression) RNF125 C036990 CTD decreases(expression) RNF186 C036990 CTD increases(expression) RPS6KA5 C036990 CTD increases(expression) RRM2 C036990 CTD increases(expression) S100A2 C036990 CTD decreases(expression) SERPINI2 C036990 CTD increases(expression) SHCBP1 C036990 CTD decreases(expression) SLC15A1 C036990 CTD decreases(expression) SLC2A14 C036990 CTD increases(expression) SLC7A11 C036990 CTD decreases(expression) SMYD3 C036990 CTD decreases(expression) SPDYE1 C036990 CTD decreases(expression) TAS2R20 C036990 CTD increases(expression) TBC1D25 C036990 CTD increases(expression) TNFSF9 C036990 CTD increases(expression) TOP2A C036990 CTD increases(expression) TP53 C036990 CTD decreases(expression) TRAPPC9 C036990 CTD increases(expression) TRIM63 C036990 CTD increases(expression) TRIM72 C036990 CTD increases(expression) UBE2J2 C036990 CTD increases(expression) UGT1A1 C036990 CTD increases(expression) UHRF1 C036990 CTD decreases(expression) VAMP1 C036990 CTD decreases(expression) VIL1 C036990 CTD increases(expression) WASL C036990 CTD decreases(expression) YAP1 C036990 CTD increases(expression) ZNF343 C036990 CTD increases(expression) ZNF799 C036990
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