Tan Lab | DSigDB

Gene Set: D4 : CTD - desethylamiodarone

Collection

D4 : CTD

Chemical Name

desethylamiodarone ( From PubChem : DESETHYLAMIODARONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
617.258 g/mol	1	4	6.5948	False(2/4)

Structure

InChI

InChI=1S/C23H25I2NO3/c1-3-5-9-20-21(16-8-6-7-10-19(16)29-20)22(27)15-13-17(24)23(18(25)14-15)28-12-11-26-4-2/h6-8,10,13-14,26H,3-5,9,11-12H2,1-2H3

InChIKey

Links

Gene (9 / 27)

⊖ Less

Source	Type	Gene	Other
CTD	decreases(reaction)	ABCB1	C036116
CTD	increases(transport)	ABCB1	C036116
CTD	decreases(activity)	ABCB1	C036116
CTD	increases(expression)	AGT	C036116
CTD	affects(cotreatment)	CXCL8	C036116
CTD	increases(expression)	CXCL8	C036116
CTD	increases(secretion)	CXCL8	C036116
CTD	decreases(reaction)	CXCL8	C036116
CTD	increases(chemical synthesis)	CYP3A4	C036116
CTD	increases(metabolic processing)	CYP3A4	C036116
CTD	affects(cotreatment)	CYP3A4	C036116
CTD	increases(expression)	CYP3A4	C036116
CTD	increases(secretion)	CYP3A4	C036116
CTD	decreases(reaction)	CYP3A4	C036116
CTD	affects(cotreatment)	ICAM1	C036116
CTD	increases(expression)	ICAM1	C036116
CTD	increases(expression)	LDLR	C036116
CTD	increases(reaction)	LDLR	C036116
CTD	decreases(expression)	LDLR	C036116
CTD	increases(chemical synthesis)	NOS3	C036116
CTD	increases(reaction)	NOS3	C036116
CTD	affects(binding)	THRB	C036116
CTD	decreases(reaction)	THRB	C036116
CTD	affects(cotreatment)	TNF	C036116
CTD	increases(expression)	TNF	C036116
CTD	increases(secretion)	TNF	C036116
CTD	decreases(reaction)	TNF	C036116

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