Tan Lab | DSigDB

Gene Set: D4 : CTD - 2,2',4,4'-tetrahydroxybenzophenone

Collection

D4 : CTD

Chemical Name

2,2',4,4'-tetrahydroxybenzophenone ( From PubChem : 2,2',4,4'-TETRAHYDROXYBENZOPHENONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
246.215 g/mol	4	5	1.74	True

Structure

InChI

InChI=1S/C13H10O5/c14-7-1-3-9(11(16)5-7)13(18)10-4-2-8(15)6-12(10)17/h1-6,14-17H

InChIKey

Links

Gene (7 / 19)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			ESR1		C035476
CTD	increases(activity)			ESR1		C035476
CTD	affects(binding)			ESR1		C035476
CTD	affects(binding)			ESR2		C035476
CTD	increases(activity)			ESR2		C035476
CTD	affects(binding)			ESR2		C035476
CTD	decreases(activity)			TPO		C035476
PubChem	AhR Potency (uM)	uM	11.738	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.690	AHR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	34.721	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	4.332	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	9.770	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	10.980	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	13.821	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	15.355	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	18.765	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	47.198	HSPB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	51.868	HSPB1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	24.580	NR3C1	-	GI(Protien) :

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