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Gene Set: D4 : CTD - catechol

Collection D4 : CTD
Chemical Name catechol ( From PubChem : CATECHOL )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotApprovedNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
110.111 g/mol 2 2 1.0978 True
Structure
InChI InChI=1S/C6H6O2/c7-5-3-1-2-4-6(5)8/h1-4,7-8H
InChIKey YCIMNLLNPGFGHC-UHFFFAOYSA-N
Links

Gene (46 / 100)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDaffects(cotreatment)ALAS2
C034221
CTDincreases(expression)ALAS2
C034221
CTDdecreases(reaction)ALAS2
C034221
CTDincreases(expression)ALAS2
C034221
CTDdecreases(reaction)CASP3
C034221
CTDincreases(activity)CASP3
C034221
CTDdecreases(reaction)CASP7
C034221
CTDincreases(activity)CASP7
C034221
CTDincreases(expression)CCL11
C034221
CTDincreases(expression)CCL2
C034221
CTDincreases(expression)CCL3
C034221
CTDincreases(expression)CCL4
C034221
CTDincreases(expression)CCL5
C034221
CTDaffects(cotreatment)COMT
C034221
CTDdecreases(reaction)COMT
C034221
CTDincreases(expression)COMT
C034221
CTDincreases(abundance)COMT
C034221
CTDincreases(response to substance)COMT
C034221
CTDincreases(methylation)COMT
C034221
CTDincreases(expression)CXCL8
C034221
CTDaffects(chemical synthesis)CYP2E1
C034221
CTDaffects(metabolic processing)CYP2E1
C034221
CTDincreases(expression)GATA1
C034221
CTDaffects(cotreatment)HBB
C034221
CTDincreases(expression)HBB
C034221
CTDdecreases(reaction)HBB
C034221
CTDdecreases(methylation)HBB
C034221
CTDincreases(expression)HBB
C034221
CTDaffects(cotreatment)HMBS
C034221
CTDincreases(expression)HMBS
C034221
CTDdecreases(reaction)HMBS
C034221
CTDdecreases(methylation)HMBS
C034221
CTDincreases(expression)HMBS
C034221
CTDaffects(cotreatment)IL10
C034221
CTDdecreases(reaction)IL10
C034221
CTDincreases(expression)IL10
C034221
CTDdecreases(reaction)MYC
C034221
CTDincreases(expression)MYC
C034221
CTDincreases(expression)NQO1
C034221
CTDincreases(sulfation)SULT1A1
C034221
CTDincreases(sulfation)SULT1A2
C034221
CTDincreases(sulfation)SULT1A3
C034221
CTDincreases(sulfation)SULT1C2
C034221
CTDdecreases(reaction)TFRC
C034221
CTDincreases(expression)TFRC
C034221
PubChem AhR Potency (uM)uM28.374AHR-GI(Protien) :
PubChem AhR Potency (uM)uM43.806AHR-GI(Protien) :
PubChem Potency-Replicate_1uM49.151AHR-GI(Protien) :
PubChem Potency-Replicate_1uM61.131AHR-GI(Protien) :
PubChem PotencyuM14.125ALDH1A1-GI(Protien) :
PubChem PotencyuM17.783ALDH1A1-GI(Protien) :
PubChem PotencyuM15.849ALOX15-GI(Protien) :
PubChem Potency-Replicate_1uM27.640CYP19A1-GI(Protien) :
PubChem PotencyuM1.259EHMT2-GI(Protien) :
PubChem PotencyuM1.585EHMT2-GI(Protien) :
PubChem PotencyuM1.778EHMT2-GI(Protien) :
PubChem PotencyuM5.012ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM49.560ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM52.516ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM54.954ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM61.645ESR1-GI(Protien) :
PubChem PotencyuM5.973FEN1-GI(Protien) :
PubChem PotencyuM5.973FEN1-GI(Protien) :
PubChem PotencyuM1.995GLS-GI(Protien) :
PubChem PotencyuM12.589HIF1A-GI(Protien) :
PubChem PotencyuM11.220HPGD-GI(Protien) :
PubChem PotencyuM17.783HPGD-GI(Protien) :
PubChem NoneuMHSP90AA1-GI(Protien) :
PubChem PotencyuM17.783L3MBTL1-GI(Protien) :
PubChem PotencyuM79.433MPHOSPH8-GI(Protien) :
PubChem PotencyuM10.399MTOR-GI(Protien) :
PubChem Ratio Potency (uM)uM20.477NFE2L2-GI(Protien) :
PubChem PotencyuM29.849NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM30.638NFE2L2-GI(Protien) :
PubChem Ratio Potency (uM)uM39.951NFE2L2-GI(Protien) :
PubChem PotencyuM35.481NR3C1-GI(Protien) :
PubChem PotencyuM39.811POLB-GI(Protien) :
PubChem PotencyuM79.433POLI-GI(Protien) :
PubChem PotencyuM50.119POLK-GI(Protien) :
ChEMBLPotencynM17782.800ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM14125.400ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM15848.900ALOX15
-Target : CHEMBL2903
ChEMBLPotencynM35481.300APEX1
-Target : CHEMBL5619
ChEMBLPotencynM28183.800APEX1
-Target : CHEMBL5619
ChEMBLPotencynM1258.900EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM1778.300EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM1584.900EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM5972.800FEN1
-Target : CHEMBL5027
ChEMBLPotencynM12589.300HIF1A
-Target : CHEMBL4261
ChEMBLPotencynM17782.800HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM11220.200HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM1584.900HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM2511.900HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM39810.700KDM4A
-Target : CHEMBL5896
ChEMBLPotencynM14125.400KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM17782.800L3MBTL1
-Target : CHEMBL1287622
ChEMBLPotencynM79432.800MPHOSPH8
-Target : CHEMBL1741210
ChEMBLPotencynM10399.200MTOR
-Target : CHEMBL2842
ChEMBLPotencynM39810.700POLB
-Target : CHEMBL2392
ChEMBLPotencynM15848.900RECQL
-Target : CHEMBL1293236
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