Tan Lab | DSigDB

Gene Set: D4 : CTD - puerarin

Collection

D4 : CTD

Chemical Name

puerarin ( From PubChem : PUERARIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
416.378 g/mol	6	9	0.3861	False(3/4)

Structure

InChI

InChI=1S/C21H20O9/c22-7-14-17(26)18(27)19(28)21(30-14)15-13(24)6-5-11-16(25)12(8-29-20(11)15)9-1-3-10(23)4-2-9/h1-6,8,14,17-19,21-24,26-28H,7H2/t14-,17-,18+,19-,21+/m1/s1

InChIKey

HKEAFJYKMMKDOR-VPRICQMDSA-N

Links

Gene (58 / 82)

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Source	Type	Unit	Gene	PMID	Other
CTD	increases(expression)		ACLY		C033607
CTD	decreases(reaction)		AKT1		C033607
CTD	increases(phosphorylation)		AKT1		C033607
CTD	increases(expression)		AQP1		C033607
CTD	increases(expression)		AQP3		C033607
CTD	decreases(expression)		AR		C033607
CTD	increases(expression)		BAX		C033607
CTD	decreases(expression)		BCL2		C033607
CTD	increases(reaction)		BCL2		C033607
CTD	decreases(expression)		BCL2		C033607
CTD	decreases(expression)		BIRC5		C033607
CTD	increases(reaction)		BIRC5		C033607
CTD	increases(expression)		CASP3		C033607
CTD	increases(reaction)		CASP3		C033607
CTD	increases(activity)		CASP3		C033607
CTD	increases(expression)		CASP8		C033607
CTD	increases(reaction)		CASP8		C033607
CTD	increases(expression)		CDH1		C033607
CTD	increases(expression)		COX1		C033607
CTD	decreases(expression)		CYGB		C033607
CTD	decreases(expression)		DSG3		C033607
CTD	decreases(expression)		EGF		C033607
CTD	decreases(activity)		ESR2		C033607
CTD	decreases(expression)		ESR2		C033607
CTD	increases(expression)		FASLG		C033607
CTD	increases(reaction)		FASLG		C033607
CTD	decreases(expression)		FBN1		C033607
CTD	decreases(expression)		FBN2		C033607
CTD	increases(expression)		FGF1		C033607
CTD	increases(expression)		FOS		C033607
CTD	decreases(expression)		HAS1		C033607
CTD	increases(expression)		HSPB1		C033607
CTD	decreases(reaction)		ICAM1		C033607
CTD	increases(expression)		ICAM1		C033607
CTD	decreases(expression)		IGF1		C033607
CTD	decreases(expression)		IL1A		C033607
CTD	decreases(expression)		KL		C033607
CTD	increases(phosphorylation)		MAPK1		C033607
CTD	increases(phosphorylation)		MAPK3		C033607
CTD	increases(expression)		MAPK8		C033607
CTD	increases(reaction)		MAPK8		C033607
CTD	increases(phosphorylation)		MAPK8		C033607
CTD	increases(phosphorylation)		MAPK9		C033607
CTD	decreases(expression)		MC1R		C033607
CTD	decreases(expression)		MYC		C033607
CTD	decreases(expression)		NOS2		C033607
CTD	decreases(reaction)		NOS3		C033607
CTD	increases(phosphorylation)		NOS3		C033607
CTD	increases(abundance)		NOS3		C033607
CTD	increases(activity)		NOS3		C033607
CTD	increases(expression)		NOS3		C033607
CTD	decreases(expression)		PGR		C033607
CTD	increases(expression)		PGR		C033607
CTD	increases(expression)		PLOD3		C033607
CTD	decreases(expression)		PML		C033607
CTD	increases(reaction)		PML		C033607
CTD	decreases(expression)		PPARG		C033607
CTD	decreases(expression)		PTGER1		C033607
CTD	decreases(expression)		RARA		C033607
CTD	increases(reaction)		RARA		C033607
CTD	increases(expression)		RARA		C033607
CTD	decreases(reaction)		RELA		C033607
CTD	increases(expression)		RELA		C033607
CTD	decreases(expression)		SOD3		C033607
CTD	decreases(expression)		SRD5A2		C033607
CTD	decreases(expression)		TERT		C033607
CTD	decreases(reaction)		TNF		C033607
CTD	increases(expression)		TNF		C033607
CTD	decreases(activity)		TNF		C033607
CTD	increases(expression)		TPT1		C033607
CTD	increases(expression)		TXN		C033607
CTD	decreases(expression)		TYRP1		C033607
CTD	increases(metabolic processing)		UGT1A1		C033607
CTD	increases(metabolic processing)		UGT1A10		C033607
CTD	increases(metabolic processing)		UGT1A3		C033607
CTD	increases(metabolic processing)		UGT1A6		C033607
CTD	increases(metabolic processing)		UGT1A7		C033607
CTD	increases(metabolic processing)		UGT1A8		C033607
CTD	increases(metabolic processing)		UGT1A9		C033607
PubChem	None	uM	GFER	-	GI(Protien) :
PubChem	None	uM	GFER	-	GI(Protien) :
ChEMBL	Activity	-	ESR1	-	Target : CHEMBL206

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