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Gene Set: D4 : CTD - afloqualone

Collection D4 : CTD
Chemical Name afloqualone ( From PubChem : AFLOQUALONE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotApprovedNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
283.3 g/mol 1 4 3.327 True
Structure
InChI InChI=1S/C16H14FN3O/c1-10-4-2-3-5-14(10)20-15(9-17)19-13-7-6-11(18)8-12(13)16(20)21/h2-8H,9,18H2,1H3
InChIKey VDOSWXIDETXFET-UHFFFAOYSA-N
Links

Gene (5 / 9)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDincreases(glucuronidation)UGT1A3
C033541
CTDdecreases(reaction)UGT1A4
C033541
CTDincreases(glucuronidation)UGT1A4
C033541
PubChem AhR Potency (uM)uM28.180AHR-GI(Protien) :
PubChem Potency-Replicate_1uM29.849AHR-GI(Protien) :
PubChem Potency-Replicate_1uM26.603AR-GI(Protien) :
PubChem Potency-Replicate_1uM21.314ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM22.555ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM26.603ESR1-GI(Protien) :
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