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Drug SIGnatures DataBase

Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - naphthalene

Collection

D4 : CTD

Chemical Name

naphthalene ( From PubChem : NAPHTHALENE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
128.171 g/mol	0	0	2.8398	True

Structure

InChI

InChI=1S/C10H8/c1-2-6-10-8-4-3-7-9(10)5-1/h1-8H

InChIKey

UFWIBTONFRDIAS-UHFFFAOYSA-N

Links

Gene (42 / 57)

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Source	Type	Unit	Value	Gene	PMID	Assay	Other
CTD	decreases(activity)			ABCB1			C031721
CTD	affects(cotreatment)			AHR			C031721
CTD	increases(activity)			AHR			C031721
CTD	decreases(expression)			ASCL1			C031721
CTD	decreases(reaction)			ASCL1			C031721
CTD	increases(expression)			ASCL1			C031721
CTD	increases(expression)			BCL2			C031721
CTD	affects(binding)			CASP9			C031721
CTD	increases(expression)			CASP9			C031721
CTD	increases(expression)			CXCL8			C031721
CTD	increases(expression)			CYP1A1			C031721
CTD	decreases(activity)			CYP1A2			C031721
CTD	decreases(reaction)			CYP1A2			C031721
CTD	increases(chemical synthesis)			CYP1A2			C031721
CTD	increases(metabolic processing)			CYP1A2			C031721
CTD	decreases(activity)			CYP1A2			C031721
CTD	affects(binding)			CYP1B1			C031721
CTD	decreases(activity)			CYP1B1			C031721
CTD	increases(expression)			CYP2C19			C031721
CTD	increases(expression)			CYP2C8			C031721
CTD	increases(expression)			CYP2C9			C031721
CTD	increases(expression)			CYP2D6			C031721
CTD	increases(expression)			CYP2E1			C031721
CTD	affects(metabolic processing)			CYP2S1			C031721
CTD	increases(expression)			CYP3A4			C031721
CTD	increases(expression)			CYP3A5			C031721
CTD	increases(expression)			EPHX1			C031721
CTD	increases(expression)			EPHX2			C031721
CTD	decreases(expression)			FGF7			C031721
CTD	decreases(response to substance)			FGF7			C031721
CTD	increases(expression)			FOS			C031721
CTD	decreases(expression)			FUS			C031721
CTD	affects(binding)			GCGR			C031721
CTD	decreases(activity)			GCGR			C031721
CTD	increases(expression)			GSTM1			C031721
CTD	increases(expression)			IER3			C031721
CTD	increases(expression)			IL4			C031721
CTD	increases(expression)			JUN			C031721
CTD	increases(expression)			LGALS1			C031721
CTD	affects(binding)			MC1R			C031721
CTD	affects(binding)			MC3R			C031721
CTD	affects(binding)			MC4R			C031721
CTD	affects(binding)			MC5R			C031721
CTD	decreases(expression)			NDC80			C031721
CTD	decreases(reaction)			NOS3			C031721
CTD	increases(expression)			NOS3			C031721
CTD	decreases(expression)			PAH			C031721
CTD	increases(expression)			RAF1			C031721
CTD	increases(expression)			RHOC			C031721
CTD	decreases(expression)			SCGB1A1			C031721
CTD	decreases(reaction)			SCGB1A1			C031721
CTD	decreases(reaction)			SYP			C031721
CTD	increases(expression)			SYP			C031721
CTD	increases(expression)			TCF7			C031721
CTD	increases(expression)			TIMP1			C031721
CTD	affects(binding)			TP53			C031721
CTD	increases(expression)			TP53			C031721

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Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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