Tan Lab | DSigDB

Gene Set: D4 : CTD - 7-hydroxycoumarin

Collection

D4 : CTD

Chemical Name

7-hydroxycoumarin ( From PubChem : 7-HYDROXYCOUMARIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
162.142 g/mol	1	3	1.4986	True

Structure

InChI

InChI=1S/C9H6O3/c10-7-3-1-6-2-4-9(11)12-8(6)5-7/h1-5,10H

InChIKey

Links

Gene (13 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			AKR1C3		C031477
CTD	increases(response to substance)			AKR1C3		C031477
CTD	increases(expression)			AKR1C3		C031477
CTD	affects(reaction)			AKR7A2		C031477
CTD	increases(response to substance)			AKR7A2		C031477
CTD	increases(expression)			AKR7A2		C031477
CTD	increases(expression)			BAX		C031477
CTD	decreases(expression)			BCL2		C031477
CTD	decreases(expression)			CCND1		C031477
CTD	increases(chemical synthesis)			CYP2A6		C031477
CTD	affects(response to substance)			MPO		C031477
CTD	decreases(activity)			MPO		C031477
CTD	increases(oxidation)			MPO		C031477
CTD	increases(sulfation)			SULT1A1		C031477
CTD	increases(glucuronidation)			UGT1A9		C031477
CTD	increases(metabolic processing)			UGT2B15		C031477
PubChem	AC50_uM	uM	12.140	ERAP1	-	GI(Protien) :
PubChem	None	uM		ERAP1	-	GI(Protien) :
PubChem	None	uM		KLK7	-	GI(Protien) :
PubChem	None	uM		KLK7	-	GI(Protien) :
ChEMBL	Potency	nM	25118.900	HSD17B10	-	Target : CHEMBL4159

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