Tan Lab | DSigDB

Gene Set: D4 : CTD - 2,4,6-tribromophenol

Collection

D4 : CTD

Chemical Name

2,4,6-tribromophenol ( From PubChem : 2,4,6-TRIBROMOPHENOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
330.799 g/mol	1	1	3.6797	True

Structure

InChI

InChI=1S/C6H3Br3O/c7-3-1-4(8)6(10)5(9)2-3/h1-2,10H

InChIKey

Links

Gene (13 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			CYP11A1		C004554
CTD	decreases(expression)			CYP11B2		C004554
CTD	decreases(expression)			CYP17A1		C004554
CTD	increases(activity)			CYP19A1		C004554
CTD	increases(expression)			CYP19A1		C004554
CTD	decreases(expression)			CYP21A2		C004554
CTD	increases(expression)			HSD3B2		C004554
CTD	increases(expression)			STAR		C004554
CTD	increases(expression)			TFF1		C004554
CTD	increases(reaction)			TFF1		C004554
CTD	affects(binding)			TTR		C004554
PubChem	Potency	uM	15.849	CYP3A4	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	55.062	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.781	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	15.355	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	24.337	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	24.386	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	42.163	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	43.737	PPARG	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
ChEMBL	Potency	nM	15848.900	CYP3A4	-	Target : CHEMBL340

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