Tan Lab | DSigDB

Gene Set: D4 : CTD - chrysene

Collection

D4 : CTD

Chemical Name

chrysene ( From PubChem : CHRYSENE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
228.288 g/mol	0	0	5.1462	False(3/4)

Structure

InChI

InChI=1S/C18H12/c1-3-7-15-13(5-1)9-11-18-16-8-4-2-6-14(16)10-12-17(15)18/h1-12H

InChIKey

WDECIBYCCFPHNR-UHFFFAOYSA-N

Links

Gene (25 / 58)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCB1		C031180
CTD	affects(binding)			AHR		C031180
CTD	decreases(reaction)			AHR		C031180
CTD	increases(activity)			AHR		C031180
CTD	increases(expression)			AHR		C031180
CTD	affects(cotreatment)			AHR		C031180
CTD	increases(activity)			AHR		C031180
CTD	increases(reaction)			AHR		C031180
CTD	increases(expression)			AHR		C031180
CTD	increases(reaction)			AHR		C031180
CTD	increases(expression)			AKR1C1		C031180
CTD	affects(binding)			AR		C031180
CTD	decreases(activity)			AR		C031180
CTD	decreases(reaction)			AR		C031180
CTD	increases(activity)			AR		C031180
CTD	decreases(activity)			AR		C031180
CTD	increases(activity)			CASP3		C031180
CTD	decreases(activity)			CAT		C031180
CTD	affects(binding)			CYP1A1		C031180
CTD	decreases(reaction)			CYP1A1		C031180
CTD	increases(activity)			CYP1A1		C031180
CTD	increases(expression)			CYP1A1		C031180
CTD	increases(expression)			CYP1A1		C031180
CTD	increases(reaction)			CYP1A1		C031180
CTD	increases(expression)			CYP1A1		C031180
CTD	affects(cotreatment)			CYP1A1		C031180
CTD	increases(metabolic processing)			CYP1A1		C031180
CTD	increases(reaction)			CYP1A1		C031180
CTD	increases(expression)			CYP1A2		C031180
CTD	affects(cotreatment)			CYP1A2		C031180
CTD	increases(metabolic processing)			CYP1A2		C031180
CTD	increases(reaction)			CYP1A2		C031180
CTD	increases(expression)			CYP1B1		C031180
CTD	increases(metabolic processing)			EPHX1		C031180
CTD	increases(reaction)			EPHX1		C031180
CTD	affects(cotreatment)			ESR1		C031180
CTD	increases(expression)			ESR1		C031180
CTD	increases(expression)			FOS		C031180
CTD	affects(cotreatment)			GSTM1		C031180
CTD	affects(metabolic processing)			GSTM1		C031180
CTD	increases(expression)			ICAM1		C031180
CTD	increases(expression)			IER3		C031180
CTD	increases(expression)			JUN		C031180
CTD	decreases(reaction)			KLK3		C031180
CTD	increases(expression)			KLK3		C031180
CTD	increases(reaction)			KLK3		C031180
CTD	increases(expression)			LGALS1		C031180
CTD	decreases(expression)			NDC80		C031180
CTD	decreases(expression)			PAH		C031180
CTD	increases(expression)			RHOC		C031180
CTD	increases(expression)			TIMP1		C031180
CTD	increases(expression)			UGT1A6		C031180
CTD	increases(expression)			UGT1A7		C031180
PubChem	AhR Potency (uM)	uM	4.417	AHR	-	GI(Protien) :
PubChem	Potency	uM	11.220	AHR	-	GI(Protien) :
PubChem	Potency	uM	4.328	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	23.903	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	24.838	NFE2L2	-	GI(Protien) :

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