Tan Lab | DSigDB

Gene Set: D4 : CTD - AICA ribonucleotide

Collection

D4 : CTD

Chemical Name

AICA ribonucleotide ( From PubChem : IN1541 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
338.211 g/mol	6	12	-1.4258	False(2/4)

Structure

InChI

InChI=1S/C9H15N4O8P/c10-7-4(8(11)16)12-2-13(7)9-6(15)5(14)3(21-9)1-20-22(17,18)19/h2-3,5-6,9,14-15H,1,10H2,(H2,11,16)(H2,17,18,19)/t3-,5-,6+,9+/m1/s1

InChIKey

NOTGFIUVDGNKRI-ICKFSKTQSA-N

Links

Gene (23 / 50)

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Source	Type	Unit	Gene	PMID	Other
CTD	increases(phosphorylation)		ACACA		C031143
CTD	increases(phosphorylation)		ACACB		C031143
CTD	decreases(expression)		APP		C031143
CTD	decreases(expression)		ATG5		C031143
CTD	decreases(reaction)		ATG5		C031143
CTD	decreases(reaction)		CASP3		C031143
CTD	increases(cleavage)		CASP3		C031143
CTD	decreases(reaction)		CASP7		C031143
CTD	increases(cleavage)		CASP7		C031143
CTD	decreases(reaction)		CCL3		C031143
CTD	increases(expression)		CCL3		C031143
CTD	affects(binding)		CCNA2		C031143
CTD	decreases(reaction)		CCNA2		C031143
CTD	decreases(expression)		CCNA2		C031143
CTD	affects(binding)		CCNB1		C031143
CTD	decreases(reaction)		CCNB1		C031143
CTD	decreases(expression)		CCNB1		C031143
CTD	decreases(reaction)		CXCL8		C031143
CTD	increases(expression)		CXCL8		C031143
CTD	decreases(reaction)		CYP4F2		C031143
CTD	increases(expression)		CYP4F2		C031143
CTD	affects(reaction)		CYP4F2		C031143
CTD	decreases(reaction)		EGFR		C031143
CTD	increases(import)		EGFR		C031143
CTD	affects(binding)		ELAVL1		C031143
CTD	decreases(reaction)		ELAVL1		C031143
CTD	decreases(localization)		ELAVL1		C031143
CTD	decreases(activity)		INSR		C031143
CTD	decreases(reaction)		INSR		C031143
CTD	decreases(expression)		INSR		C031143
CTD	decreases(activity)		MMP2		C031143
CTD	decreases(activity)		MMP9		C031143
CTD	decreases(activity)		MTOR		C031143
CTD	increases(activity)		PRKAA1		C031143
CTD	increases(phosphorylation)		PRKAA1		C031143
CTD	increases(phosphorylation)		PRKAA1		C031143
CTD	affects(reaction)		PRKAA1		C031143
CTD	increases(expression)		PRKAA1		C031143
CTD	increases(activity)		PRKAA2		C031143
CTD	increases(phosphorylation)		PRKAA2		C031143
CTD	increases(phosphorylation)		PRKAA2		C031143
CTD	affects(reaction)		PRKAA2		C031143
CTD	increases(expression)		PRKAA2		C031143
CTD	increases(response to substance)		PTEN		C031143
CTD	decreases(phosphorylation)		RPS6		C031143
CTD	decreases(activity)		SLC15A1		C031143
ChEMBL	Activity	-	CASP3	-	Target : CHEMBL2334
ChEMBL	Activity	-	CASP3	-	Target : CHEMBL2334
ChEMBL	Activity	-	CASP9	-	Target : CHEMBL2273
ChEMBL	Activity	-	CASP9	-	Target : CHEMBL2273

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