Tan Lab | DSigDB

Gene Set: D4 : CTD - benzoquinone

Collection

D4 : CTD

Chemical Name

benzoquinone ( From PubChem : P-BENZOQUINONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
108.095 g/mol	0	2	0.2506	True

Structure

InChI

InChI=1S/C6H4O2/c7-5-1-2-6(8)4-3-5/h1-4H

InChIKey

AZQWKYJCGOJGHM-UHFFFAOYSA-N

Links

Gene (47 / 90)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			AKR1C2		C004532
CTD	affects(binding)			ALB		C004532
CTD	affects(binding)			ALB		C004532
CTD	increases(reaction)			ALB		C004532
CTD	affects(binding)			ALB		C004532
CTD	increases(expression)			BAX		C004532
CTD	decreases(expression)			BCL2		C004532
CTD	decreases(activity)			CASP3		C004532
CTD	increases(activity)			CASP3		C004532
CTD	decreases(activity)			CASP7		C004532
CTD	decreases(reaction)			CAT		C004532
CTD	increases(abundance)			CAT		C004532
CTD	increases(activity)			CAT		C004532
CTD	increases(phosphorylation)			CAT		C004532
CTD	decreases(response to substance)			CAT		C004532
CTD	increases(expression)			CCL11		C004532
CTD	increases(expression)			CCL2		C004532
CTD	increases(expression)			CCL3		C004532
CTD	increases(expression)			CCL4		C004532
CTD	increases(expression)			CCL5		C004532
CTD	increases(expression)			CDKN1A		C004532
CTD	affects(cotreatment)			CSF1R		C004532
CTD	increases(abundance)			CSF1R		C004532
CTD	increases(reaction)			CSF1R		C004532
CTD	increases(expression)			CXCL12		C004532
CTD	increases(expression)			CXCL8		C004532
CTD	increases(expression)			CXCL8		C004532
CTD	increases(secretion)			CXCL8		C004532
CTD	increases(expression)			CYP1A1		C004532
CTD	increases(reduction)			DHRS7		C004532
CTD	increases(expression)			DKK1		C004532
CTD	increases(expression)			GCLM		C004532
CTD	increases(expression)			GSS		C004532
CTD	affects(reaction)			GSS		C004532
CTD	increases(phosphorylation)			H2AFX		C004532
CTD	increases(expression)			HMOX1		C004532
CTD	affects(reaction)			HMOX1		C004532
CTD	affects(cotreatment)			IL10		C004532
CTD	decreases(reaction)			IL10		C004532
CTD	increases(expression)			IL10		C004532
CTD	increases(expression)			IL6		C004532
CTD	decreases(expression)			JAG1		C004532
CTD	affects(binding)			KDR		C004532
CTD	decreases(activity)			KDR		C004532
CTD	increases(expression)			KITLG		C004532
CTD	increases(expression)			MAFF		C004532
CTD	decreases(reaction)			MAPK1		C004532
CTD	increases(activity)			MAPK1		C004532
CTD	increases(phosphorylation)			MAPK1		C004532
CTD	decreases(reaction)			MAPK3		C004532
CTD	increases(activity)			MAPK3		C004532
CTD	increases(phosphorylation)			MAPK3		C004532
CTD	affects(binding)			MAPT		C004532
CTD	increases(reaction)			MAPT		C004532
CTD	increases(activity)			MYB		C004532
CTD	increases(expression)			MYB		C004532
CTD	increases(reaction)			MYB		C004532
CTD	affects(localization)			NFE2L2		C004532
CTD	increases(expression)			NFE2L2		C004532
CTD	affects(reaction)			NFE2L2		C004532
CTD	increases(expression)			NQO1		C004532
CTD	increases(expression)			NQO1		C004532
CTD	increases(expression)			RUNX2		C004532
CTD	affects(activity)			TOP2A		C004532
CTD	affects(binding)			TOP2A		C004532
CTD	affects(binding)			TOP2A		C004532
CTD	decreases(activity)			TOP2A		C004532
CTD	affects(activity)			TOP2A		C004532
CTD	decreases(activity)			TOP2A		C004532
CTD	increases(activity)			TOP2A		C004532
CTD	increases(expression)			TOP2A		C004532
CTD	increases(reaction)			TOP2A		C004532
CTD	increases(expression)			TP53		C004532
CTD	increases(expression)			WNT5A		C004532
PubChem	IC50_Mean	uM	36.100	APOBEC3G	-	GI(Protien) :
PubChem	None	uM		APOBEC3G	-	GI(Protien) :
PubChem	None	uM		APOBEC3G	-	GI(Protien) :
PubChem	None	uM		CCR6	-	GI(Protien) :
PubChem	None	uM		GNAI1	-	GI(Protien) :
PubChem	None	uM		HKDC1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	24.460	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	47.308	NFE2L2	-	GI(Protien) :
PubChem	None	uM		OPRM1	-	GI(Protien) :
PubChem	None	uM		RGS12	-	GI(Protien) :
PubChem	Potency	uM	10.000	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	14125.400	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	7079.500	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	14125.400	APEX1	-	Target : CHEMBL5619
ChEMBL	IC50	nM	36100.000	APOBEC3G	-	Target : CHEMBL1741217
ChEMBL	Potency	nM	17782.800	TDP1	-	Target : CHEMBL1075138

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