Tan Lab | DSigDB

Gene Set: D4 : CTD - pyrene

Collection

D4 : CTD

Chemical Name

pyrene ( From PubChem : PYRENE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
202.251 g/mol	0	0	4.584	True

Structure

InChI

InChI=1S/C16H10/c1-3-11-7-9-13-5-2-6-14-10-8-12(4-1)15(11)16(13)14/h1-10H

InChIKey

Links

Gene (16 / 34)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(cotreatment)			AHR		C030984
CTD	increases(activity)			AHR		C030984
CTD	increases(reaction)			AHR		C030984
CTD	decreases(reaction)			AR		C030984
CTD	increases(activity)			AR		C030984
CTD	increases(expression)			CXCL8		C030984
CTD	increases(secretion)			CXCL8		C030984
CTD	increases(reaction)			CXCL8		C030984
CTD	increases(expression)			CXCL8		C030984
CTD	increases(hydroxylation)			CYP1A1		C030984
CTD	affects(cotreatment)			CYP1A1		C030984
CTD	increases(expression)			CYP1A1		C030984
CTD	increases(hydroxylation)			CYP1A2		C030984
CTD	increases(hydroxylation)			CYP1B1		C030984
CTD	affects(cotreatment)			CYP1B1		C030984
CTD	increases(expression)			CYP1B1		C030984
CTD	affects(binding)			CYP1B1		C030984
CTD	decreases(activity)			CYP1B1		C030984
CTD	increases(expression)			CYP1B1		C030984
CTD	increases(expression)			HSPA1A		C030984
CTD	increases(expression)			ICAM1		C030984
CTD	affects(activity)			IFNG		C030984
CTD	increases(expression)			IL4		C030984
CTD	increases(cleavage)			PARP1		C030984
CTD	affects(binding)			TLR3		C030984
CTD	affects(response to substance)			TLR3		C030984
CTD	increases(expression)			TNF		C030984
CTD	increases(reaction)			TNF		C030984
CTD	affects(cotreatment)			UGT1A6		C030984
CTD	increases(expression)			UGT1A6		C030984
CTD	affects(cotreatment)			UGT1A7		C030984
CTD	increases(expression)			UGT1A7		C030984
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159

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