Tan Lab | DSigDB

Gene Set: D4 : CTD - benz(a)anthracene

Collection

D4 : CTD

Chemical Name

benz(a)anthracene ( From PubChem : BENZ[A]ANTHRACENE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
228.288 g/mol	0	0	5.1462	False(3/4)

Structure

InChI

InChI=1S/C18H12/c1-2-7-15-12-18-16(11-14(15)6-1)10-9-13-5-3-4-8-17(13)18/h1-12H

InChIKey

DXBHBZVCASKNBY-UHFFFAOYSA-N

Links

Gene (69 / 175)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(cotreatment)			AHR		C030935
CTD	affects(reaction)			AHR		C030935
CTD	increases(expression)			AHR		C030935
CTD	increases(activity)			AHR		C030935
CTD	increases(reaction)			AHR		C030935
CTD	affects(binding)			AHR		C030935
CTD	affects(cotreatment)			AHR		C030935
CTD	increases(activity)			AHR		C030935
CTD	increases(reaction)			AHR		C030935
CTD	increases(activity)			AHR		C030935
CTD	increases(expression)			AHR		C030935
CTD	increases(reaction)			AHR		C030935
CTD	increases(activity)			AHR		C030935
CTD	increases(expression)			AKR1B10		C030935
CTD	increases(expression)			AKR1C1		C030935
CTD	increases(expression)			AKR1C3		C030935
CTD	affects(binding)			AR		C030935
CTD	decreases(activity)			AR		C030935
CTD	increases(expression)			AREG		C030935
CTD	decreases(reaction)			AREG		C030935
CTD	increases(reaction)			AREG		C030935
CTD	increases(expression)			BTG2		C030935
CTD	affects(cotreatment)			CCL2		C030935
CTD	increases(expression)			CCL2		C030935
CTD	increases(expression)			CDKN1A		C030935
CTD	decreases(expression)			CELSR2		C030935
CTD	decreases(expression)			CLDN17		C030935
CTD	decreases(expression)			COL2A1		C030935
CTD	decreases(expression)			COL4A6		C030935
CTD	increases(expression)			CXCL12		C030935
CTD	decreases(reaction)			CXCL12		C030935
CTD	affects(cotreatment)			CXCL8		C030935
CTD	increases(expression)			CXCL8		C030935
CTD	increases(activity)			CYP1A1		C030935
CTD	increases(reaction)			CYP1A1		C030935
CTD	decreases(reaction)			CYP1A1		C030935
CTD	increases(expression)			CYP1A1		C030935
CTD	increases(expression)			CYP1A1		C030935
CTD	increases(reaction)			CYP1A1		C030935
CTD	increases(activity)			CYP1A1		C030935
CTD	increases(expression)			CYP1A1		C030935
CTD	increases(expression)			CYP1A1		C030935
CTD	decreases(reaction)			CYP1A1		C030935
CTD	increases(activity)			CYP1A1		C030935
CTD	affects(reaction)			CYP1A1		C030935
CTD	increases(expression)			CYP1A1		C030935
CTD	affects(cotreatment)			CYP1A1		C030935
CTD	increases(metabolic processing)			CYP1A1		C030935
CTD	increases(metabolic processing)			CYP1A1		C030935
CTD	increases(reaction)			CYP1A1		C030935
CTD	decreases(reaction)			CYP1A1		C030935
CTD	increases(expression)			CYP1A1		C030935
CTD	decreases(activity)			CYP1A2		C030935
CTD	increases(expression)			CYP1A2		C030935
CTD	affects(cotreatment)			CYP1A2		C030935
CTD	increases(metabolic processing)			CYP1A2		C030935
CTD	increases(reaction)			CYP1A2		C030935
CTD	affects(reaction)			CYP1B1		C030935
CTD	increases(expression)			CYP1B1		C030935
CTD	decreases(reaction)			CYP1B1		C030935
CTD	increases(expression)			CYP1B1		C030935
CTD	affects(cotreatment)			CYP1B1		C030935
CTD	increases(expression)			CYP1B1		C030935
CTD	increases(expression)			CYP1B1		C030935
CTD	increases(metabolic processing)			EPHX1		C030935
CTD	increases(reaction)			EPHX1		C030935
CTD	decreases(expression)			ERBB2		C030935
CTD	increases(expression)			ERCC1		C030935
CTD	increases(activity)			ESR1		C030935
CTD	increases(reaction)			ESR1		C030935
CTD	increases(expression)			ESR1		C030935
CTD	increases(phosphorylation)			ESR1		C030935
CTD	affects(cotreatment)			ESR1		C030935
CTD	decreases(reaction)			ESR1		C030935
CTD	decreases(reaction)			ETS1		C030935
CTD	increases(expression)			ETS1		C030935
CTD	increases(expression)			FGF9		C030935
CTD	decreases(expression)			FREM1		C030935
CTD	increases(expression)			GADD45A		C030935
CTD	increases(expression)			IER3		C030935
CTD	increases(expression)			IL1A		C030935
CTD	decreases(expression)			IL1B		C030935
CTD	affects(cotreatment)			IL6		C030935
CTD	affects(reaction)			IL6		C030935
CTD	increases(expression)			IL6		C030935
CTD	increases(secretion)			IL6		C030935
CTD	increases(expression)			IL6		C030935
CTD	increases(secretion)			IL6		C030935
CTD	decreases(reaction)			IL6		C030935
CTD	increases(expression)			IL6		C030935
CTD	increases(reaction)			IL6		C030935
CTD	decreases(reaction)			ITGA2		C030935
CTD	increases(expression)			ITGA2		C030935
CTD	decreases(reaction)			JUN		C030935
CTD	increases(expression)			JUN		C030935
CTD	increases(expression)			LGALS1		C030935
CTD	decreases(reaction)			MAPK14		C030935
CTD	increases(phosphorylation)			MAPK14		C030935
CTD	increases(expression)			MIR1180		C030935
CTD	increases(expression)			MIR1275		C030935
CTD	increases(expression)			MIR1301		C030935
CTD	increases(expression)			MIR181D		C030935
CTD	increases(expression)			MIR198		C030935
CTD	increases(expression)			MIR200C		C030935
CTD	increases(expression)			MIR22		C030935
CTD	increases(expression)			MIR221		C030935
CTD	increases(expression)			MIR23B		C030935
CTD	decreases(expression)			MIR33A		C030935
CTD	increases(expression)			MIR629		C030935
CTD	increases(expression)			MIR658		C030935
CTD	increases(expression)			MIRLET7B		C030935
CTD	decreases(reaction)			MMP2		C030935
CTD	increases(expression)			MMP2		C030935
CTD	decreases(expression)			NDC80		C030935
CTD	affects(cotreatment)			NEDD9		C030935
CTD	increases(expression)			NEDD9		C030935
CTD	affects(cotreatment)			NFKBIA		C030935
CTD	increases(degradation)			NFKBIA		C030935
CTD	increases(phosphorylation)			NFKBIA		C030935
CTD	increases(activity)			NQO1		C030935
CTD	increases(expression)			NQO1		C030935
CTD	decreases(expression)			PAH		C030935
CTD	increases(cleavage)			PARP1		C030935
CTD	increases(expression)			PGR		C030935
CTD	decreases(reaction)			PGR		C030935
CTD	increases(expression)			POLH		C030935
CTD	affects(cotreatment)			PRKCD		C030935
CTD	affects(response to substance)			PRKCD		C030935
CTD	decreases(activity)			PRKCD		C030935
CTD	decreases(reaction)			PRKCD		C030935
CTD	increases(expression)			PRKCD		C030935
CTD	increases(reaction)			PRKCD		C030935
CTD	affects(cotreatment)			PTGS2		C030935
CTD	increases(expression)			PTGS2		C030935
CTD	affects(cotreatment)			RELA		C030935
CTD	affects(reaction)			RELA		C030935
CTD	increases(expression)			RELA		C030935
CTD	increases(expression)			RHOC		C030935
CTD	decreases(expression)			SHC3		C030935
CTD	decreases(reaction)			SNAI1		C030935
CTD	increases(expression)			SNAI1		C030935
CTD	decreases(reaction)			TFF1		C030935
CTD	increases(expression)			TFF1		C030935
CTD	increases(reaction)			TFF1		C030935
CTD	decreases(activity)			TFF1		C030935
CTD	affects(cotreatment)			TGFB1		C030935
CTD	increases(expression)			TGFB1		C030935
CTD	increases(expression)			TIMP1		C030935
CTD	decreases(expression)			TLN2		C030935
CTD	affects(cotreatment)			TNF		C030935
CTD	affects(reaction)			TNF		C030935
CTD	increases(expression)			TNF		C030935
CTD	increases(activity)			TNF		C030935
CTD	affects(cotreatment)			TNF		C030935
CTD	increases(expression)			TNF		C030935
CTD	increases(degradation)			TNF		C030935
CTD	increases(phosphorylation)			TNF		C030935
CTD	increases(secretion)			TNF		C030935
CTD	decreases(reaction)			TNF		C030935
CTD	decreases(expression)			VAV3		C030935
PubChem	Potency-Replicate_1	uM	4.341	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	4.856	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	6.859	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	11.331	AHR	-	GI(Protien) :
PubChem	Potency	uM	22.387	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	68.590	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.558	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	54.649	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	55.136	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	55.136	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	6.113	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	8.021	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	10.461	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	12.197	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	30.638	NFE2L2	-	GI(Protien) :

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