Tan Lab | DSigDB

Gene Set: D4 : CTD - tryptamine

Collection

D4 : CTD

Chemical Name

tryptamine ( From PubChem : TRYPTAMINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
160.216 g/mol	2	1	2.3694	True

Structure

InChI

InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2

InChIKey

Links

Gene (19 / 42)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			CYP2A6		C030820
CTD	decreases(abundance)			CYP2A6		C030820
CTD	decreases(activity)			CYP2A6		C030820
CTD	decreases(response to substance)			HTR2A		C030820
CTD	affects(response to substance)			HTR2A		C030820
CTD	affects(binding)			HTR2A		C030820
CTD	increases(activity)			HTR2A		C030820
CTD	decreases(reaction)			SLC6A2		C030820
CTD	increases(activity)			SLC6A2		C030820
CTD	increases(reaction)			SLC6A2		C030820
CTD	decreases(reaction)			SLC6A3		C030820
CTD	increases(activity)			SLC6A3		C030820
CTD	increases(reaction)			SLC6A3		C030820
CTD	decreases(reaction)			SLC6A4		C030820
CTD	increases(activity)			SLC6A4		C030820
CTD	increases(reaction)			SLC6A4		C030820
CTD	decreases(reaction)			TAAR1		C030820
CTD	increases(activity)			TAAR1		C030820
CTD	increases(reaction)			TAAR1		C030820
PubChem	None	uM		ADRBK1	-	GI(Protien) :
PubChem	Average IC50	uM	1.660	APOBEC3G	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1F		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR5A	-	GI(Protien) :
PubChem	None	uM		HTR7		GI(Protien) :
PubChem	None	uM		MAP4K2	-	GI(Protien) :
PubChem	Potency	uM	12.589	NFKB1	-	GI(Protien) :
ChEMBL	AC50	nM	3162.280	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	12589.300	NFKB1	-	Target : CHEMBL3251

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