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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 2-amino-3-methylimidazo(4,5-f)quinoline

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Collection	D4 : CTD
Chemical Name	2-amino-3-methylimidazo(4,5-f)quinoline ( From PubChem : 76180-96-6 )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 198.224 g/mol 1 4 2.2849 True
Structure
InChI	InChI=1S/C11H10N4/c1-15-9-5-4-8-7(3-2-6-13-8)10(9)14-11(15)12/h2-6H,1H3,(H2,12,14)
InChIKey	ARZWATDYIYAUTA-UHFFFAOYSA-N
Links
Gene (18 / 35) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(mutagenesis) APRT C029216 CTD increases(response to substance) APRT C029216 CTD decreases(expression) BAX C546460 CTD increases(expression) BCL2 C546460 CTD increases(expression) CDKN1A C546460 CTD increases(expression) CYP1A1 C546460 CTD affects(activity) CYP1A1 C029216 CTD increases(expression) CYP1A2 C546460 CTD affects(metabolic processing) CYP1A2 C029216 CTD affects(cotreatment) CYP1A2 C029216 CTD increases(response to substance) CYP1A2 C029216 CTD increases(activity) CYP1A2 C029216 CTD increases(activity) CYP1A2 C029216 CTD increases(hydroxylation) CYP1A2 C029216 CTD increases(activity) CYP1A2 C029216 CTD affects(cotreatment) CYP3A7 C029216 CTD increases(response to substance) CYP3A7 C029216 CTD decreases(expression) GSTA1 C546460 CTD decreases(expression) MDM2 C546460 CTD decreases(expression) NAT2 C546460 CTD affects(cotreatment) NAT2 C029216 CTD increases(response to substance) NAT2 C029216 CTD increases(response to substance) NAT2 C029216 CTD increases(mutagenesis) NAT2 C029216 CTD affects(cotreatment) OAT C029216 CTD increases(response to substance) OAT C029216 CTD affects(cotreatment) POR C029216 CTD increases(response to substance) POR C029216 CTD increases(metabolic processing) PTGS1 C029216 CTD increases(metabolic processing) PTGS2 C029216 CTD increases(expression) RRM2B C029216 CTD increases(expression) TP53 C546460 CTD increases(expression) UGT1A1 C546460 PubChem Potency-Replicate_1 uM 4.615 AHR - GI(Protien) : PubChem AhR Potency (uM) uM 8.527 AHR - GI(Protien) :
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