Tan Lab | DSigDB

Gene Set: D4 : CTD - danthron

Collection

D4 : CTD

Chemical Name

danthron ( From PubChem : DANTHRON )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Approved	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
240.211 g/mol	2	4	1.8732	True

Structure

InChI

InChI=1S/C14H8O4/c15-9-5-1-3-7-11(9)14(18)12-8(13(7)17)4-2-6-10(12)16/h1-6,15-16H

InChIKey

QBPFLULOKWLNNW-UHFFFAOYSA-N

Links

Gene (33 / 54)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			AHR		C004315
CTD	increases(activity)			AHR		C004315
CTD	affects(localization)			AIFM1		C004315
CTD	increases(expression)			AIFM1		C004315
CTD	affects(binding)			ALB		C004315
CTD	increases(expression)			ATF6		C004315
CTD	increases(expression)			BAX		C004315
CTD	decreases(expression)			BCL2		C004315
CTD	decreases(expression)			BCL2L1		C004315
CTD	increases(expression)			BCL2L1		C004315
CTD	increases(expression)			BID		C004315
CTD	decreases(expression)			BIRC2		C004315
CTD	increases(expression)			BIRC3		C004315
CTD	decreases(expression)			BIRC5		C004315
CTD	decreases(reaction)			CASP3		C004315
CTD	increases(activity)			CASP3		C004315
CTD	increases(expression)			CASP3		C004315
CTD	decreases(reaction)			CASP8		C004315
CTD	increases(activity)			CASP8		C004315
CTD	increases(expression)			CASP8		C004315
CTD	decreases(reaction)			CASP9		C004315
CTD	increases(activity)			CASP9		C004315
CTD	increases(expression)			CASP9		C004315
CTD	affects(localization)			CYCS		C004315
CTD	increases(expression)			CYCS		C004315
CTD	increases(expression)			DDIT3		C004315
CTD	increases(expression)			DIABLO		C004315
CTD	affects(localization)			ENDOG		C004315
CTD	increases(expression)			ENDOG		C004315
CTD	increases(expression)			FAS		C004315
CTD	increases(expression)			FASLG		C004315
CTD	increases(expression)			HSPA5		C004315
CTD	decreases(expression)			SOD1		C004315
CTD	decreases(expression)			SOD2		C004315
CTD	increases(expression)			TNFSF10		C004315
CTD	decreases(expression)			XIAP		C004315
PubChem	None	uM		BCL2L1	-	GI(Protien) :
PubChem	None	uM		BCL2L1	-	GI(Protien) :
PubChem	None	uM		CASP1	-	GI(Protien) :
PubChem	Potency	uM	3.548	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	7.943	EHMT2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	30.950	ESR1	-	GI(Protien) :
PubChem	Potency	uM	35.481	HPGD	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	19.528	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	26.601	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	29.849	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NLRP1	-	GI(Protien) :
PubChem	None	uM		NLRP3	-	GI(Protien) :
PubChem	None	uM		NLRP3	-	GI(Protien) :
ChEMBL	Potency	nM	7943.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	3548.100	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	35481.300	HPGD	-	Target : CHEMBL1293255

Download gene sets

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