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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 1,4-bis(2-(3,5-dichloropyridyloxy))benzene

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Collection	D4 : CTD
Chemical Name	1,4-bis(2-(3,5-dichloropyridyloxy))benzene ( From PubChem : TCPOBOP )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 402.059 g/mol 0 4 6.6748 False(3/4)
Structure
InChI	InChI=1S/C16H8Cl4N2O2/c17-9-5-13(19)15(21-7-9)23-11-1-2-12(4-3-11)24-16-14(20)6-10(18)8-22-16/h1-8H
InChIKey	BAFKRPOFIYPKBQ-UHFFFAOYSA-N
Links
Gene (14 / 52) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(expression) CYP1A2 C028474 CTD increases(reaction) CYP1A2 C028474 CTD affects(binding) CYP2B6 C028474 CTD increases(reaction) CYP2B6 C028474 CTD decreases(reaction) CYP2B6 C028474 CTD affects(binding) CYP3A4 C028474 CTD increases(reaction) CYP3A4 C028474 CTD affects(binding) CYP3A4 C028474 CTD increases(reaction) CYP3A4 C028474 CTD decreases(reaction) HNF4A C028474 CTD increases(expression) HNF4A C028474 CTD affects(binding) NCOA1 C028474 CTD affects(cotreatment) NCOA1 C028474 CTD increases(reaction) NCOA1 C028474 CTD affects(binding) NCOA6 C028474 CTD increases(activity) NCOA6 C028474 CTD increases(reaction) NCOA6 C028474 CTD decreases(reaction) NCOA6 C028474 CTD increases(expression) NCOA6 C028474 CTD increases(activity) NR1I2 C028474 CTD affects(binding) NR1I3 C028474 CTD affects(cotreatment) NR1I3 C028474 CTD increases(reaction) NR1I3 C028474 CTD affects(binding) NR1I3 C028474 CTD increases(reaction) NR1I3 C028474 CTD affects(binding) NR1I3 C028474 CTD increases(activity) NR1I3 C028474 CTD increases(reaction) NR1I3 C028474 CTD decreases(activity) NR1I3 C028474 CTD increases(activity) NR1I3 C028474 CTD increases(activity) NR1I3 C028474 CTD increases(expression) NR1I3 C028474 CTD decreases(reaction) NR1I3 C028474 CTD affects(reaction) NR1I3 C028474 CTD decreases(expression) NR1I3 C028474 CTD affects(binding) RXRA C028474 CTD affects(cotreatment) RXRA C028474 CTD increases(reaction) RXRA C028474 CTD affects(binding) RXRA C028474 CTD increases(reaction) RXRA C028474 CTD decreases(reaction) UGT2B7 C028474 CTD increases(expression) UGT2B7 C028474 CTD decreases(expression) UGT2B7 C028474 CTD affects(reaction) UGT2B7 C028474 PubChem IC50_Mean uM 0.368 CRHBP - GI(Protien) : PubChem IC50_Mean uM 18.000 CRHBP - GI(Protien) : PubChem None uM CRHBP - GI(Protien) : PubChem IC50_Mean uM 0.368 CRHR2 - GI(Protien) : PubChem IC50_Mean uM 18.000 CRHR2 - GI(Protien) : PubChem None uM CRHR2 - GI(Protien) : PubChem Potency uM 12.589 ESR1 - GI(Protien) : PubChem None uM MRGPRX1 - GI(Protien) :
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