Tan Lab | DSigDB

Gene Set: D4 : CTD - 3',4'-dihydroxyflavone

Collection

D4 : CTD

Chemical Name

3',4'-dihydroxyflavone ( From PubChem : 3',4'-DIHYDROXYFLAVONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
254.238 g/mol	2	4	2.8712	True

Structure

InChI

InChI=1S/C15H10O4/c16-11-6-5-9(7-13(11)18)15-8-12(17)10-3-1-2-4-14(10)19-15/h1-8,16,18H

InChIKey

Links

Gene (12 / 18)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			ABCC1		C028288
PubChem	Potency	uM	25.119	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	1.585	ALOX15	-	GI(Protien) :
PubChem	Potency	uM	15.849	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	7.080	HPGD	-	GI(Protien) :
PubChem	Potency	uM	7.943	MAPK1	-	GI(Protien) :
PubChem	Potency	uM	17.783	MAPT	-	GI(Protien) :
PubChem	Potency	uM	14.125	POLK	-	GI(Protien) :
PubChem	Potency	uM	14.125	SMN2	-	GI(Protien) :
ChEMBL	Potency	nM	25118.900	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	1584.900	ALOX15	-	Target : CHEMBL2903
ChEMBL	Potency	nM	15848.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	7079.500	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	5011.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	8912.500	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	7943.300	MAPK1	-	Target : CHEMBL4040
ChEMBL	Potency	nM	17782.800	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	14125.400	SMN1; SMN2	-	Target : CHEMBL1293232

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