Tan Lab | DSigDB

Gene Set: D4 : CTD - diallyl disulfide

Collection

D4 : CTD

Chemical Name

diallyl disulfide ( From PubChem : DIALLYL DISULFIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
146.274 g/mol	0	2	2.7398	True

Structure

InChI

InChI=1S/C6H10S2/c1-3-5-7-8-6-4-2/h3-4H,1-2,5-6H2

InChIKey

PFRGXCVKLLPLIP-UHFFFAOYSA-N

Links

Gene (42 / 65)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCB1		C028009
CTD	decreases(expression)			ABCC1		C028009
CTD	increases(expression)			ABCC1		C028009
CTD	affects(expression)			ABCC3		C028009
CTD	increases(expression)			ABCC3		C028009
CTD	decreases(expression)			ABCC4		C028009
CTD	increases(expression)			ABCC4		C028009
CTD	decreases(expression)			ABCC6		C028009
CTD	increases(expression)			ABCC6		C028009
CTD	increases(expression)			ATF3		C028009
CTD	decreases(expression)			BCL2		C028009
CTD	increases(activity)			CASP3		C028009
CTD	increases(activity)			CASP9		C028009
CTD	affects(binding)			CAV1		C028009
CTD	increases(reaction)			CAV1		C028009
CTD	decreases(expression)			CCNB1		C028009
CTD	increases(expression)			CCNB1		C028009
CTD	decreases(expression)			CDH1		C028009
CTD	decreases(expression)			CDK1		C028009
CTD	decreases(expression)			CLDN2		C028009
CTD	decreases(expression)			CLDN3		C028009
CTD	decreases(expression)			CLDN4		C028009
CTD	decreases(expression)			CLDN5		C028009
CTD	increases(expression)			CTNNB1		C028009
CTD	decreases(activity)			CYP1A1		C028009
CTD	decreases(activity)			CYP2A6		C028009
CTD	decreases(activity)			CYP2E1		C028009
CTD	increases(expression)			GDF15		C028009
CTD	affects(reaction)			GDF15		C028009
CTD	affects(expression)			GRB2		C028009
CTD	decreases(expression)			GRB2		C028009
CTD	increases(phosphorylation)			JUN		C028009
CTD	affects(expression)			MAP2K7		C028009
CTD	affects(expression)			MAP3K3		C028009
CTD	decreases(expression)			MAPK1		C028009
CTD	decreases(expression)			MAPK3		C028009
CTD	increases(phosphorylation)			MAPK8		C028009
CTD	decreases(activity)			MMP2		C028009
CTD	decreases(expression)			MMP2		C028009
CTD	decreases(expression)			MMP2		C028009
CTD	decreases(expression)			MMP7		C028009
CTD	affects(expression)			MMP9		C028009
CTD	decreases(activity)			MMP9		C028009
CTD	decreases(expression)			MMP9		C028009
CTD	affects(expression)			NOS2		C028009
CTD	affects(binding)			NOS3		C028009
CTD	increases(reaction)			NOS3		C028009
CTD	decreases(degradation)			NOS3		C028009
CTD	increases(expression)			NOS3		C028009
CTD	increases(phosphorylation)			NOS3		C028009
CTD	decreases(reaction)			NOS3		C028009
CTD	affects(expression)			PTGS2		C028009
CTD	decreases(expression)			SNAI1		C028009
CTD	increases(expression)			TIMP1		C028009
CTD	increases(expression)			TIMP2		C028009
CTD	decreases(reaction)			TP53		C028009
CTD	increases(expression)			TP53		C028009
CTD	increases(expression)			TP53		C028009
CTD	affects(reaction)			TP53		C028009
CTD	increases(expression)			TP53		C028009
PubChem	Potency	uM	6.310	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	8.912	HPGD	-	GI(Protien) :
PubChem	Potency	uM	19.953	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	6309.600	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	8912.500	HPGD	-	Target : CHEMBL1293255

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