Tan Lab | DSigDB

Gene Set: D4 : CTD - indirubin

Collection

D4 : CTD

Chemical Name

indirubin ( From PubChem : CHEMBL35349 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
262.263 g/mol	2	4	2.9342	True

Structure

InChI

InChI=1S/C16H10N2O2/c19-15-10-6-2-4-8-12(10)17-14(15)13-9-5-1-3-7-11(9)18-16(13)20/h1-8,17H,(H,18,20)/b14-13-

InChIKey

CRDNMYFJWFXOCH-YPKPFQOOSA-N

Links

Gene (41 / 56)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
CTD	decreases(expression)		ACADSB		C027185
CTD	affects(binding)		AHR		C027185
CTD	affects(binding)		AHR		C027185
CTD	increases(activity)		AHR		C027185
CTD	increases(activity)		AHR		C027185
CTD	decreases(expression)		ARF4		C027185
CTD	increases(activity)		ARNT		C027185
CTD	decreases(expression)		CCT4		C027185
CTD	decreases(expression)		CDH2		C027185
CTD	decreases(expression)		CDK1		C027185
CTD	decreases(reaction)		CDK2		C027185
CTD	increases(phosphorylation)		CDK2		C027185
CTD	decreases(activity)		CDK2		C027185
CTD	decreases(expression)		CLK1		C027185
CTD	decreases(expression)		COPS2		C027185
CTD	increases(expression)		CSF3R		C027185
CTD	increases(secretion)		CXCL8		C027185
CTD	increases(expression)		CXCR1		C027185
CTD	increases(expression)		CYP19A1		C027185
CTD	increases(metabolic processing)		CYP1A1		C027185
CTD	affects(binding)		CYP1A1		C027185
CTD	decreases(activity)		CYP1A1		C027185
CTD	decreases(reaction)		CYP1A1		C027185
CTD	increases(activity)		CYP1A1		C027185
CTD	increases(activity)		CYP1A1		C027185
CTD	increases(expression)		CYP1A1		C027185
CTD	increases(expression)		CYP1A2		C027185
CTD	increases(metabolic processing)		CYP1B1		C027185
CTD	increases(expression)		CYP1B1		C027185
CTD	increases(expression)		CYR61		C027185
CTD	decreases(expression)		E2F1		C027185
CTD	increases(expression)		GSTP1		C027185
CTD	decreases(expression)		HSBP1		C027185
CTD	decreases(expression)		HSPD1		C027185
CTD	decreases(expression)		HSPH1		C027185
CTD	decreases(expression)		IFNG		C027185
CTD	increases(expression)		IGFBP1		C027185
CTD	decreases(expression)		IL1R1		C027185
CTD	decreases(expression)		ILF2		C027185
CTD	decreases(expression)		ITGB1		C027185
CTD	increases(expression)		ITGB2		C027185
CTD	decreases(expression)		MGST2		C027185
CTD	decreases(expression)		MSH2		C027185
CTD	increases(expression)		NCF1		C027185
CTD	increases(expression)		NPC1		C027185
CTD	decreases(reaction)		RB1		C027185
CTD	increases(phosphorylation)		RB1		C027185
CTD	decreases(expression)		SEPT2		C027185
CTD	decreases(expression)		SLC2A2		C027185
CTD	increases(activity)		SPI1		C027185
CTD	decreases(expression)		TCF12		C027185
CTD	decreases(expression)		TOP1		C027185
CTD	decreases(expression)		TOP2A		C027185
PubChem	None	uM	AHR	-	GI(Protien) :
PubChem	None	uM	NCF1	-	GI(Protien) :
PubChem	None	uM	WEE1	-	GI(Protien) :

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