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Gene Set: D4 : CTD - 1,2,5,6-dibenzanthracene

Collection D4 : CTD
Chemical Name 1,2,5,6-dibenzanthracene ( From PubChem : DIBENZ[A,H]ANTHRACENE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
278.347 g/mol 0 0 6.2994 False(3/4)
Structure
InChI InChI=1S/C22H14/c1-3-7-19-15(5-1)9-11-17-14-22-18(13-21(17)19)12-10-16-6-2-4-8-20(16)22/h1-14H
InChIKey LHRCREOYAASXPZ-UHFFFAOYSA-N
Links

Gene (78 / 162)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDaffects(cotreatment)A2M
C026486
CTDaffects(expression)A2M
C026486
CTDaffects(localization)AHR
C026486
CTDaffects(binding)AHR
C026486
CTDincreases(activity)AHR
C026486
CTDaffects(binding)AHR
C026486
CTDdecreases(reaction)AHR
C026486
CTDincreases(expression)AHR
C026486
CTDincreases(reaction)AHR
C026486
CTDaffects(cotreatment)AHR
C026486
CTDincreases(activity)AHR
C026486
CTDdecreases(reaction)AHR
C026486
CTDaffects(cotreatment)AKR1B1
C026486
CTDaffects(expression)AKR1B1
C026486
CTDincreases(expression)AKR1C1
C026486
CTDaffects(cotreatment)ALDOB
C026486
CTDaffects(expression)ALDOB
C026486
CTDaffects(cotreatment)AMACR
C026486
CTDaffects(expression)AMACR
C026486
CTDaffects(cotreatment)APOC3
C026486
CTDaffects(expression)APOC3
C026486
CTDaffects(binding)AR
C026486
CTDincreases(activity)AR
C026486
CTDaffects(cotreatment)ATF3
C026486
CTDaffects(expression)ATF3
C026486
CTDincreases(expression)ATG4C
C026486
CTDdecreases(expression)BCL2L1
C026486
CTDincreases(expression)BCL3
C026486
CTDaffects(cotreatment)CA3
C026486
CTDaffects(expression)CA3
C026486
CTDincreases(expression)CEACAM5
C026486
CTDincreases(expression)CP
C026486
CTDdecreases(expression)CRABP2
C026486
CTDincreases(expression)CYB5A
C026486
CTDincreases(expression)CYP1A1
C026486
CTDincreases(reaction)CYP1A1
C026486
CTDincreases(activity)CYP1A1
C026486
CTDincreases(expression)CYP1A1
C026486
CTDincreases(expression)CYP1A1
C026486
CTDdecreases(reaction)CYP1A1
C026486
CTDincreases(activity)CYP1A1
C026486
CTDaffects(cotreatment)CYP1A1
C026486
CTDaffects(expression)CYP1A1
C026486
CTDdecreases(reaction)CYP1A1
C026486
CTDincreases(activity)CYP1A1
C026486
CTDaffects(cotreatment)CYP1A1
C026486
CTDincreases(metabolic processing)CYP1A1
C026486
CTDincreases(reaction)CYP1A1
C026486
CTDdecreases(activity)CYP1A2
C026486
CTDincreases(activity)CYP1A2
C026486
CTDincreases(expression)CYP1A2
C026486
CTDdecreases(reaction)CYP1A2
C026486
CTDaffects(cotreatment)CYP1A2
C026486
CTDaffects(expression)CYP1A2
C026486
CTDaffects(cotreatment)CYP1A2
C026486
CTDincreases(metabolic processing)CYP1A2
C026486
CTDincreases(metabolic processing)CYP1A2
C026486
CTDincreases(chemical synthesis)CYP1A2
C026486
CTDincreases(reaction)CYP1A2
C026486
CTDincreases(expression)CYP1B1
C026486
CTDincreases(expression)CYP1B1
C026486
CTDaffects(cotreatment)CYP2B6
C026486
CTDaffects(expression)CYP2B6
C026486
CTDincreases(metabolic processing)CYP2B6
C026486
CTDincreases(chemical synthesis)CYP2B6
C026486
CTDincreases(metabolic processing)CYP2C9
C026486
CTDincreases(chemical synthesis)CYP2C9
C026486
CTDincreases(expression)CYP2D6
C026486
CTDincreases(expression)CYP2E1
C026486
CTDdecreases(expression)DBI
C026486
CTDaffects(cotreatment)ECE1
C026486
CTDaffects(expression)ECE1
C026486
CTDincreases(metabolic processing)EPHX1
C026486
CTDincreases(reaction)EPHX1
C026486
CTDdecreases(expression)ERBB2
C026486
CTDaffects(cotreatment)FABP1
C026486
CTDaffects(expression)FABP1
C026486
CTDaffects(cotreatment)FASN
C026486
CTDaffects(expression)FASN
C026486
CTDaffects(cotreatment)FGA
C026486
CTDaffects(expression)FGA
C026486
CTDincreases(expression)FGF9
C026486
CTDaffects(cotreatment)FGG
C026486
CTDaffects(expression)FGG
C026486
CTDaffects(cotreatment)FMO5
C026486
CTDaffects(expression)FMO5
C026486
CTDaffects(cotreatment)G6PD
C026486
CTDaffects(expression)G6PD
C026486
CTDaffects(cotreatment)GCK
C026486
CTDaffects(expression)GCK
C026486
CTDaffects(metabolic processing)GSTA1
C026486
CTDdecreases(response to substance)GSTA1
C026486
CTDaffects(cotreatment)GSTM1
C026486
CTDaffects(metabolic processing)GSTM1
C026486
CTDincreases(expression)HAMP
C026486
CTDincreases(activity)HIF1A
C026486
CTDaffects(cotreatment)HIF1A
C026486
CTDaffects(expression)HIF1A
C026486
CTDdecreases(expression)HMGCR
C026486
CTDaffects(cotreatment)HMGCR
C026486
CTDaffects(expression)HMGCR
C026486
CTDincreases(expression)ID2
C026486
CTDincreases(expression)IER3
C026486
CTDincreases(expression)IGF1
C026486
CTDaffects(cotreatment)IGF1
C026486
CTDaffects(expression)IGF1
C026486
CTDaffects(cotreatment)IGF2
C026486
CTDaffects(expression)IGF2
C026486
CTDincreases(expression)IGFBP1
C026486
CTDaffects(cotreatment)IGFBP1
C026486
CTDaffects(expression)IGFBP1
C026486
CTDincreases(expression)LGALS1
C026486
CTDincreases(expression)LGALS3
C026486
CTDincreases(expression)MAPT
C026486
CTDaffects(cotreatment)MCL1
C026486
CTDaffects(expression)MCL1
C026486
CTDaffects(cotreatment)MT1E
C026486
CTDaffects(expression)MT1E
C026486
CTDdecreases(expression)NDC80
C026486
CTDincreases(expression)NFKBIA
C026486
CTDdecreases(expression)NGFR
C026486
CTDincreases(expression)NQO1
C026486
CTDdecreases(expression)PAH
C026486
CTDincreases(expression)PCNA
C026486
CTDincreases(expression)PIM1
C026486
CTDincreases(expression)RAD52
C026486
CTDincreases(expression)RECQL
C026486
CTDincreases(expression)RHOC
C026486
CTDaffects(cotreatment)SAT1
C026486
CTDaffects(expression)SAT1
C026486
CTDaffects(cotreatment)SCD
C026486
CTDaffects(expression)SCD
C026486
CTDaffects(cotreatment)SERPINA3
C026486
CTDaffects(expression)SERPINA3
C026486
CTDincreases(expression)SLC2A1
C026486
CTDaffects(cotreatment)SPP1
C026486
CTDaffects(expression)SPP1
C026486
CTDdecreases(expression)TGM2
C026486
CTDincreases(expression)TIMP1
C026486
CTDincreases(activity)TPO
C026486
CTDaffects(cotreatment)TYROBP
C026486
CTDaffects(expression)TYROBP
C026486
CTDincreases(expression)UBD
C026486
CTDaffects(cotreatment)UBE2A
C026486
CTDaffects(expression)UBE2A
C026486
CTDdecreases(expression)UQCRB
C026486
CTDincreases(expression)VAT1
C026486
CTDincreases(expression)VMP1
C026486
PubChem Potency-Replicate_1uM0.121AHR-GI(Protien) :
PubChem AhR Potency (uM)uM0.130AHR-GI(Protien) :
PubChem Potency-Replicate_1uM0.958AHR-GI(Protien) :
PubChem AhR Potency (uM)uM1.074AHR-GI(Protien) :
PubChem PotencyuM2.818AHR-GI(Protien) :
PubChem Ratio Potency (uM)uM7.687ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM19.306ESR1-GI(Protien) :
PubChem PotencyuM44.668HIF1A-GI(Protien) :
PubChem Potency-Replicate_1uM0.538NFE2L2-GI(Protien) :
PubChem Ratio Potency (uM)uM0.678NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM0.959NFE2L2-GI(Protien) :
PubChem Ratio Potency (uM)uM1.076NFE2L2-GI(Protien) :
PubChem PotencyuM2.371NFE2L2-GI(Protien) :
PubChem PotencyuM39.811THRB-GI(Protien) :
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