Tan Lab | DSigDB

Gene Set: D4 : CTD - sorbinil

Collection

D4 : CTD

Chemical Name

sorbinil ( From PubChem : SORBINIL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
236.199 g/mol	2	5	1.3005	True

Structure

InChI

InChI=1S/C11H9FN2O3/c12-6-1-2-8-7(5-6)11(3-4-17-8)9(15)13-10(16)14-11/h1-2,5H,3-4H2,(H2,13,14,15,16)/t11-/m0/s1

InChIKey

Links

Gene (8 / 20)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
CTD	decreases(activity)		AKR1B1		C026411
CTD	decreases(reaction)		AKR1B1		C026411
CTD	increases(abundance)		AKR1B1		C026411
CTD	increases(secretion)		AKR1B1		C026411
CTD	decreases(response to substance)		AKR1B1		C026411
CTD	decreases(reaction)		AKR1B10		C026411
CTD	increases(reduction)		AKR1B10		C026411
CTD	decreases(activity)		AKR1B10		C026411
CTD	decreases(reaction)		CXCL8		C026411
CTD	increases(secretion)		CXCL8		C026411
CTD	decreases(reaction)		IL6		C026411
CTD	increases(secretion)		IL6		C026411
CTD	decreases(reaction)		TNF		C026411
CTD	increases(abundance)		TNF		C026411
CTD	increases(secretion)		TNF		C026411
CTD	decreases(activity)		TNF		C026411
CTD	decreases(response to substance)		TNF		C026411
ChEMBL	Inhibition	-	NFKB1	-	Target : CHEMBL2094258
ChEMBL	Inhibition	-	NFKB2	-	Target : CHEMBL2094258
ChEMBL	Inhibition	-	RELA	-	Target : CHEMBL2094258

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