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Gene Set: D4 : CTD - torsemide

Collection D4 : CTD
Chemical Name torsemide ( From PubChem : TORASEMIDE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedNotApprovedNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
348.42 g/mol 3 6 4.4655 True
Structure
InChI InChI=1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)
InChIKey NGBFQHCMQULJNZ-UHFFFAOYSA-N
Links

Gene (6 / 13)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDincreases(metabolic processing)CYP2C8
C026116
CTDdecreases(activity)CYP2C8
C026116
CTDdecreases(reaction)CYP2C8
C026116
CTDincreases(hydroxylation)CYP2C9
C026116
CTDincreases(metabolic processing)CYP2C9
C026116
PubChem PotencyuM12.589CYP3A4-GI(Protien) :
ChEMBLInhibition-CYP1A2
-Target : CHEMBL3356
ChEMBLInhibition-CYP2C19
-Target : CHEMBL3622
ChEMBLInhibition-CYP2C9
-Target : CHEMBL3397
ChEMBLInhibition-CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM12589.300CYP3A4
-Target : CHEMBL340
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
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