Tan Lab | DSigDB

Gene Set: D4 : CTD - 22-hydroxycholesterol

Collection

D4 : CTD

Chemical Name

22-hydroxycholesterol ( From PubChem : 22-HYDROXYCHOLESTEROL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
402.653 g/mol	2	2	6.3595	False(3/4)

Structure

InChI

InChI=1S/C27H46O2/c1-17(2)6-11-25(29)18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20-,21-,22+,23-,24-,25+,26-,27+/m0/s1

InChIKey

RZPAXNJLEKLXNO-GFKLAVDKSA-N

Links

Gene (45 / 86)

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Source	Type	Gene	Other
CTD	increases(expression)	ABCA1	C003585
CTD	affects(cotreatment)	ABCA1	C003585
CTD	increases(expression)	ABCA1	C003585
CTD	decreases(reaction)	ABCA1	C003585
CTD	increases(expression)	ABCG1	C003585
CTD	increases(expression)	ACKR3	C003585
CTD	increases(expression)	CAV1	C003585
CTD	affects(binding)	CCL2	C003585
CTD	affects(cotreatment)	CCL2	C003585
CTD	decreases(reaction)	CCL2	C003585
CTD	increases(reaction)	CCL2	C003585
CTD	increases(expression)	CCL2	C003585
CTD	increases(expression)	CETP	C003585
CTD	affects(cotreatment)	CETP	C003585
CTD	increases(expression)	CXCL1	C003585
CTD	increases(expression)	CXCL11	C003585
CTD	increases(expression)	CXCL2	C003585
CTD	increases(expression)	CXCL8	C003585
CTD	decreases(expression)	CYP51A1	C003585
CTD	decreases(expression)	DHCR7	C003585
CTD	increases(expression)	EGR1	C003585
CTD	affects(binding)	ESR1	C003585
CTD	decreases(activity)	ESR1	C003585
CTD	decreases(reaction)	ESR1	C003585
CTD	increases(activity)	ESR1	C003585
CTD	affects(binding)	ESR2	C003585
CTD	decreases(activity)	ESR2	C003585
CTD	decreases(reaction)	ESR2	C003585
CTD	increases(activity)	ESR2	C003585
CTD	decreases(expression)	FDFT1	C003585
CTD	increases(expression)	FOS	C003585
CTD	decreases(expression)	HMGCR	C003585
CTD	decreases(expression)	HMGCS1	C003585
CTD	increases(expression)	HMOX1	C003585
CTD	increases(expression)	ICAM1	C003585
CTD	increases(reaction)	ICAM1	C003585
CTD	decreases(expression)	IDI1	C003585
CTD	increases(expression)	IFIT2	C003585
CTD	affects(binding)	IFNG	C003585
CTD	affects(cotreatment)	IFNG	C003585
CTD	decreases(reaction)	IFNG	C003585
CTD	increases(reaction)	IFNG	C003585
CTD	increases(expression)	IFNG	C003585
CTD	increases(localization)	IFNG	C003585
CTD	increases(phosphorylation)	IFNG	C003585
CTD	increases(expression)	IL1A	C003585
CTD	decreases(expression)	LDLR	C003585
CTD	increases(expression)	LPL	C003585
CTD	affects(cotreatment)	LPL	C003585
CTD	decreases(expression)	LSS	C003585
CTD	increases(expression)	MAF	C003585
CTD	decreases(expression)	MSMO1	C003585
CTD	decreases(expression)	MVD	C003585
CTD	decreases(expression)	MVK	C003585
CTD	decreases(expression)	NOS3	C003585
CTD	affects(cotreatment)	NR1H2	C003585
CTD	affects(localization)	NR1H2	C003585
CTD	affects(binding)	NR1H3	C003585
CTD	increases(activity)	NR1H3	C003585
CTD	decreases(reaction)	NR1H3	C003585
CTD	increases(expression)	NR1H3	C003585
CTD	increases(expression)	NR1H3	C003585
CTD	increases(reaction)	NR1H3	C003585
CTD	affects(cotreatment)	NR1H3	C003585
CTD	affects(localization)	NR1H3	C003585
CTD	increases(expression)	NR5A1	C003585
CTD	increases(reaction)	NR5A1	C003585
CTD	decreases(expression)	NSDHL	C003585
CTD	increases(expression)	PTGS2	C003585
CTD	increases(expression)	SELE	C003585
CTD	increases(reaction)	SELE	C003585
CTD	decreases(expression)	SQLE	C003585
CTD	increases(expression)	STAR	C003585
CTD	increases(reaction)	STAR	C003585
CTD	affects(binding)	STAT1	C003585
CTD	affects(cotreatment)	STAT1	C003585
CTD	decreases(reaction)	STAT1	C003585
CTD	increases(reaction)	STAT1	C003585
CTD	increases(expression)	STAT1	C003585
CTD	increases(localization)	STAT1	C003585
CTD	increases(phosphorylation)	STAT1	C003585
CTD	increases(expression)	TNF	C003585
CTD	increases(reaction)	TNF	C003585
CTD	increases(expression)	TNFSF15	C003585
CTD	increases(expression)	VCAM1	C003585
CTD	increases(reaction)	VCAM1	C003585

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