Tan Lab | DSigDB

Gene Set: D4 : CTD - ochratoxin A

Collection

D4 : CTD

Chemical Name

ochratoxin A ( From PubChem : OCHRATOXIN A )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
403.813 g/mol	3	7	2.9636	True

Structure

InChI

InChI=1S/C20H18ClNO6/c1-10-7-12-14(21)9-13(17(23)16(12)20(27)28-10)18(24)22-15(19(25)26)8-11-5-3-2-4-6-11/h2-6,9-10,15,23H,7-8H2,1H3,(H,22,24)(H,25,26)/t10-,15+/m1/s1

InChIKey

RWQKHEORZBHNRI-BMIGLBTASA-N

Links

Gene (297 / 407)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(transport)			ABCA8		C025589
CTD	decreases(reaction)			ABCA8		C025589
CTD	increases(uptake)			ABCA8		C025589
CTD	decreases(expression)			ABCB6		C025589
CTD	affects(export)			ABCC2		C025589
CTD	affects(transport)			ABCC2		C025589
CTD	decreases(reaction)			ABCC2		C025589
CTD	decreases(expression)			ABCG1		C025589
CTD	decreases(expression)			ACAA1		C025589
CTD	increases(expression)			ACRC		C025589
CTD	increases(expression)			AHR		C025589
CTD	decreases(expression)			AIFM1		C025589
CTD	decreases(reaction)			AIFM1		C025589
CTD	increases(expression)			AK2		C025589
CTD	decreases(expression)			AKR1C1		C025589
CTD	decreases(expression)			AKR1C2		C025589
CTD	decreases(expression)			AKR1C3		C025589
CTD	decreases(transport)			ALB		C025589
CTD	increases(expression)			ALDH8A1		C025589
CTD	increases(expression)			ALDH8A1		C025589
CTD	decreases(expression)			ALG13		C025589
CTD	increases(expression)			AOC3		C025589
CTD	decreases(expression)			APAF1		C025589
CTD	decreases(expression)			APOL1		C025589
CTD	decreases(expression)			ARFGEF1		C025589
CTD	decreases(expression)			ARL4C		C025589
CTD	decreases(expression)			ARL5A		C025589
CTD	decreases(expression)			ARRDC3		C025589
CTD	decreases(expression)			ASNS		C025589
CTD	decreases(expression)			ATP2A2		C025589
CTD	increases(expression)			ATP5B		C025589
CTD	increases(expression)			ATP5D		C025589
CTD	increases(expression)			ATP5J		C025589
CTD	increases(expression)			AVIL		C025589
CTD	decreases(expression)			B3GNT2		C025589
CTD	decreases(expression)			B4GALT7		C025589
CTD	decreases(reaction)			BAD		C025589
CTD	increases(expression)			BAD		C025589
CTD	decreases(expression)			BAK1		C025589
CTD	increases(response to substance)			BAX		C025589
CTD	decreases(expression)			BAX		C025589
CTD	decreases(reaction)			BAX		C025589
CTD	affects(localization)			BAX		C025589
CTD	decreases(expression)			BAX		C025589
CTD	increases(expression)			BAX		C025589
CTD	decreases(expression)			BBC3		C025589
CTD	decreases(response to substance)			BCL2		C025589
CTD	decreases(expression)			BCL2		C025589
CTD	decreases(expression)			BCL2		C025589
CTD	decreases(response to substance)			BCL2L1		C025589
CTD	decreases(expression)			BCL2L1		C025589
CTD	decreases(expression)			BCL2L1		C025589
CTD	decreases(expression)			BID		C025589
CTD	decreases(expression)			BIRC3		C025589
CTD	decreases(expression)			BLCAP		C025589
CTD	decreases(expression)			BNIP3L		C025589
CTD	decreases(reaction)			BNIP3L		C025589
CTD	increases(expression)			BNIP3L		C025589
CTD	increases(reaction)			BNIP3L		C025589
CTD	increases(response to substance)			BNIP3L		C025589
CTD	increases(expression)			BZRAP1		C025589
CTD	decreases(expression)			C15ORF39		C025589
CTD	decreases(expression)			C2ORF3		C025589
CTD	increases(expression)			C9		C025589
CTD	decreases(expression)			CASP3		C025589
CTD	increases(activity)			CASP3		C025589
CTD	increases(activity)			CASP3		C025589
CTD	increases(cleavage)			CASP3		C025589
CTD	increases(cleavage)			CASP3		C025589
CTD	decreases(expression)			CASP7		C025589
CTD	decreases(expression)			CASP8		C025589
CTD	decreases(expression)			CASP9		C025589
CTD	increases(reaction)			CASP9		C025589
CTD	decreases(expression)			CASP9		C025589
CTD	increases(activity)			CASP9		C025589
CTD	increases(activity)			CASP9		C025589
CTD	increases(cleavage)			CASP9		C025589
CTD	increases(cleavage)			CASP9		C025589
CTD	increases(expression)			CAT		C025589
CTD	decreases(expression)			CCL14		C025589
CTD	affects(binding)			CCNB1		C025589
CTD	decreases(reaction)			CCNB1		C025589
CTD	decreases(expression)			CCNB1		C025589
CTD	increases(reaction)			CCNB1		C025589
CTD	affects(binding)			CCNB1		C025589
CTD	decreases(reaction)			CCNB1		C025589
CTD	decreases(expression)			CCNB1		C025589
CTD	decreases(expression)			CCNB1		C025589
CTD	decreases(expression)			CCNG1		C025589
CTD	decreases(expression)			CCNG2		C025589
CTD	decreases(expression)			CD24		C025589
CTD	decreases(expression)			CD2BP2		C025589
CTD	decreases(expression)			CD69		C025589
CTD	decreases(expression)			CDC25C		C025589
CTD	decreases(reaction)			CDC25C		C025589
CTD	increases(reaction)			CDC25C		C025589
CTD	decreases(expression)			CDC25C		C025589
CTD	decreases(expression)			CDC25C		C025589
CTD	affects(binding)			CDK1		C025589
CTD	decreases(reaction)			CDK1		C025589
CTD	decreases(expression)			CDK1		C025589
CTD	increases(reaction)			CDK1		C025589
CTD	affects(binding)			CDK1		C025589
CTD	decreases(reaction)			CDK1		C025589
CTD	decreases(expression)			CDK1		C025589
CTD	decreases(expression)			CDK1		C025589
CTD	decreases(expression)			CDKN1A		C025589
CTD	decreases(expression)			CDKN1A		C025589
CTD	decreases(expression)			CEBPA		C025589
CTD	decreases(expression)			CEBPB		C025589
CTD	decreases(expression)			CEBPB		C025589
CTD	affects(expression)			CHAC1		C025589
CTD	decreases(expression)			CHAC1		C025589
CTD	decreases(expression)			CIRBP		C025589
CTD	decreases(expression)			COMMD10		C025589
CTD	decreases(expression)			COMMD2		C025589
CTD	decreases(expression)			COQ7		C025589
CTD	increases(expression)			COX5B		C025589
CTD	increases(expression)			COX7A2L		C025589
CTD	increases(expression)			COX8A		C025589
CTD	decreases(expression)			CSRP2BP		C025589
CTD	decreases(expression)			CSTA		C025589
CTD	increases(expression)			CTNNA1		C025589
CTD	decreases(expression)			CUL7		C025589
CTD	increases(expression)			CX3CR1		C025589
CTD	decreases(reaction)			CXCL8		C025589
CTD	increases(expression)			CXCL8		C025589
CTD	decreases(expression)			CYB5R3		C025589
CTD	increases(expression)			CYBA		C025589
CTD	affects(localization)			CYCS		C025589
CTD	increases(expression)			CYP19A1		C025589
CTD	increases(response to substance)			CYP1A1		C025589
CTD	increases(expression)			CYP1A1		C025589
CTD	increases(response to substance)			CYP1A2		C025589
CTD	increases(expression)			CYP1A2		C025589
CTD	increases(expression)			CYP2B6		C025589
CTD	increases(response to substance)			CYP2C9		C025589
CTD	increases(expression)			CYP2C9		C025589
CTD	increases(response to substance)			CYP2E1		C025589
CTD	increases(response to substance)			CYP3A4		C025589
CTD	increases(expression)			CYP3A4		C025589
CTD	increases(response to substance)			CYP3A5		C025589
CTD	increases(expression)			CYP3A5		C025589
CTD	increases(expression)			DCUN1D5		C025589
CTD	decreases(expression)			DDIT3		C025589
CTD	decreases(expression)			DDIT4		C025589
CTD	decreases(expression)			DHCR7		C025589
CTD	decreases(expression)			DIABLO		C025589
CTD	decreases(expression)			DIDO1		C025589
CTD	increases(expression)			DIS3L2		C025589
CTD	decreases(expression)			DLEU2		C025589
CTD	increases(expression)			DNAJB4		C025589
CTD	decreases(expression)			DPAGT1		C025589
CTD	increases(expression)			DPY19L1		C025589
CTD	decreases(expression)			ECI1		C025589
CTD	decreases(expression)			EHD4		C025589
CTD	decreases(expression)			EML4		C025589
CTD	decreases(expression)			ENSA		C025589
CTD	decreases(expression)			EPAS1		C025589
CTD	decreases(reaction)			EPAS1		C025589
CTD	decreases(expression)			ERBB4		C025589
CTD	decreases(expression)			EVI2A		C025589
CTD	decreases(reaction)			F3		C025589
CTD	increases(expression)			F3		C025589
CTD	increases(activity)			F3		C025589
CTD	decreases(expression)			F5		C025589
CTD	decreases(expression)			FABP4		C025589
CTD	decreases(expression)			FADD		C025589
CTD	decreases(expression)			FADS1		C025589
CTD	decreases(expression)			FAHD1		C025589
CTD	decreases(expression)			FAM84A		C025589
CTD	decreases(expression)			FAS		C025589
CTD	decreases(expression)			FBXO32		C025589
CTD	increases(expression)			FGF18		C025589
CTD	increases(expression)			FOS		C025589
CTD	decreases(expression)			FRAT1		C025589
CTD	increases(expression)			FRZB		C025589
CTD	decreases(expression)			FUT6		C025589
CTD	decreases(expression)			GADD45A		C025589
CTD	increases(phosphorylation)			GJA1		C025589
CTD	increases(expression)			GNRH1		C025589
CTD	increases(expression)			GP5		C025589
CTD	increases(expression)			GPR17		C025589
CTD	increases(expression)			GPR17		C025589
CTD	decreases(expression)			GPR18		C025589
CTD	decreases(expression)			GPT2		C025589
CTD	increases(expression)			GPX1		C025589
CTD	increases(expression)			GPX3		C025589
CTD	decreases(expression)			GSTO1		C025589
CTD	increases(expression)			GTF2H5		C025589
CTD	decreases(expression)			H2AFX		C025589
CTD	increases(expression)			HBS1L		C025589
CTD	increases(expression)			HIST1H1T		C025589
CTD	decreases(expression)			HMGB2		C025589
CTD	decreases(expression)			HMOX1		C025589
CTD	increases(expression)			HSD3B1		C025589
CTD	decreases(expression)			HSPA1A		C025589
CTD	decreases(expression)			HSPA1A		C025589
CTD	increases(expression)			HSPA5		C025589
CTD	decreases(expression)			HSPA5		C025589
CTD	decreases(expression)			HSPA9		C025589
CTD	decreases(expression)			HSPB1		C025589
CTD	decreases(expression)			HYLS1		C025589
CTD	decreases(expression)			ID2		C025589
CTD	decreases(expression)			IDH3B		C025589
CTD	decreases(expression)			IDH3G		C025589
CTD	decreases(expression)			IER3		C025589
CTD	decreases(expression)			IFRD1		C025589
CTD	decreases(expression)			IGF2		C025589
CTD	decreases(expression)			IGFBP1		C025589
CTD	decreases(reaction)			IL1B		C025589
CTD	increases(expression)			IL1B		C025589
CTD	decreases(reaction)			IL1B		C025589
CTD	increases(expression)			IL1B		C025589
CTD	increases(expression)			IL1R2		C025589
CTD	decreases(expression)			ISL2		C025589
CTD	increases(expression)			JMJD6		C025589
CTD	decreases(expression)			JUN		C025589
CTD	increases(expression)			JUNB		C025589
CTD	increases(expression)			KANK1		C025589
CTD	decreases(expression)			KCNJ1		C025589
CTD	decreases(expression)			KCNJ15		C025589
CTD	decreases(expression)			KIF21B		C025589
CTD	decreases(expression)			KLF2		C025589
CTD	decreases(expression)			KLHDC2		C025589
CTD	increases(expression)			KRCC1		C025589
CTD	increases(expression)			KRT15		C025589
CTD	decreases(expression)			LPL		C025589
CTD	increases(expression)			LRRC37A3		C025589
CTD	decreases(reaction)			MAPK1		C025589
CTD	increases(phosphorylation)			MAPK1		C025589
CTD	affects(binding)			MAPK1		C025589
CTD	increases(reaction)			MAPK1		C025589
CTD	decreases(expression)			MAPK1		C025589
CTD	increases(response to substance)			MAPK1		C025589
CTD	increases(activity)			MAPK1		C025589
CTD	increases(phosphorylation)			MAPK1		C025589
CTD	affects(binding)			MAPK14		C025589
CTD	decreases(reaction)			MAPK14		C025589
CTD	increases(reaction)			MAPK14		C025589
CTD	decreases(expression)			MAPK14		C025589
CTD	increases(response to substance)			MAPK14		C025589
CTD	decreases(reaction)			MAPK3		C025589
CTD	increases(phosphorylation)			MAPK3		C025589
CTD	increases(activity)			MAPK3		C025589
CTD	increases(phosphorylation)			MAPK3		C025589
CTD	decreases(expression)			MAPRE1		C025589
CTD	increases(expression)			MBP		C025589
CTD	decreases(expression)			MED21		C025589
CTD	decreases(expression)			MPDU1		C025589
CTD	decreases(expression)			MPRIP		C025589
CTD	affects(cotreatment)			MT1A		C025589
CTD	increases(expression)			MT1A		C025589
CTD	increases(expression)			MT1A		C025589
CTD	increases(reaction)			MT1A		C025589
CTD	affects(cotreatment)			MT1B		C025589
CTD	increases(expression)			MT1B		C025589
CTD	affects(cotreatment)			MT2A		C025589
CTD	increases(expression)			MT2A		C025589
CTD	increases(expression)			MT2A		C025589
CTD	decreases(reaction)			MT2A		C025589
CTD	increases(expression)			MT2A		C025589
CTD	increases(reaction)			MT2A		C025589
CTD	decreases(expression)			MYC		C025589
CTD	decreases(expression)			NAA40		C025589
CTD	decreases(expression)			NAGA		C025589
CTD	decreases(expression)			NAGK		C025589
CTD	decreases(expression)			NANOS1		C025589
CTD	increases(expression)			NDUFA1		C025589
CTD	increases(expression)			NDUFA10		C025589
CTD	increases(expression)			NDUFA3		C025589
CTD	increases(expression)			NDUFA7		C025589
CTD	increases(expression)			NDUFB2		C025589
CTD	increases(expression)			NDUFB7		C025589
CTD	increases(expression)			NDUFC1		C025589
CTD	increases(expression)			NDUFS6		C025589
CTD	increases(expression)			NDUFS7		C025589
CTD	decreases(expression)			NFE2L3		C025589
CTD	increases(expression)			NQO1		C025589
CTD	decreases(expression)			NRG1		C025589
CTD	decreases(expression)			ORMDL2		C025589
CTD	decreases(expression)			PAPOLA		C025589
CTD	decreases(expression)			PCK2		C025589
CTD	decreases(expression)			PCNA		C025589
CTD	decreases(expression)			PDK3		C025589
CTD	decreases(expression)			PECR		C025589
CTD	decreases(expression)			PFKL		C025589
CTD	decreases(expression)			PGK1		C025589
CTD	decreases(expression)			PIGV		C025589
CTD	decreases(expression)			PIGZ		C025589
CTD	increases(expression)			PLAUR		C025589
CTD	decreases(expression)			PLIN2		C025589
CTD	decreases(expression)			PNRC1		C025589
CTD	decreases(activity)			PPARG		C025589
CTD	decreases(expression)			PPARG		C025589
CTD	increases(phosphorylation)			PPARG		C025589
CTD	decreases(expression)			PPP2R1B		C025589
CTD	decreases(expression)			PPP3CB		C025589
CTD	decreases(expression)			PREB		C025589
CTD	increases(expression)			PRG2		C025589
CTD	decreases(expression)			PROX1		C025589
CTD	decreases(expression)			PRPF4B		C025589
CTD	decreases(expression)			PTEN		C025589
CTD	decreases(expression)			RAP2B		C025589
CTD	decreases(expression)			RASGRP1		C025589
CTD	decreases(expression)			RBBP4		C025589
CTD	decreases(expression)			RFC4		C025589
CTD	decreases(expression)			RGS2		C025589
CTD	decreases(expression)			RHOB		C025589
CTD	increases(expression)			RPA1		C025589
CTD	increases(expression)			RPL13		C025589
CTD	increases(expression)			RPP30		C025589
CTD	increases(expression)			RPS15		C025589
CTD	decreases(expression)			RUFY1		C025589
CTD	decreases(expression)			S1PR1		C025589
CTD	decreases(expression)			SBF1		C025589
CTD	decreases(expression)			SC5D		C025589
CTD	decreases(expression)			SCAF8		C025589
CTD	decreases(expression)			SCD		C025589
CTD	decreases(expression)			SDHA		C025589
CTD	decreases(reaction)			SDHA		C025589
CTD	decreases(expression)			SEMA3G		C025589
CTD	decreases(reaction)			SERPINB2		C025589
CTD	increases(expression)			SERPINB2		C025589
CTD	decreases(expression)			SESN2		C025589
CTD	decreases(expression)			SGK1		C025589
CTD	decreases(expression)			SHC1		C025589
CTD	decreases(expression)			SHISA2		C025589
CTD	decreases(expression)			SLC11A2		C025589
CTD	affects(transport)			SLC22A11		C025589
CTD	increases(reaction)			SLC22A6		C025589
CTD	increases(uptake)			SLC22A6		C025589
CTD	increases(uptake)			SLC22A6		C025589
CTD	affects(transport)			SLC22A8		C025589
CTD	increases(uptake)			SLC22A8		C025589
CTD	decreases(expression)			SLC30A1		C025589
CTD	increases(reaction)			SLC30A1		C025589
CTD	decreases(reaction)			SLC30A1		C025589
CTD	affects(cotreatment)			SLC30A5		C025589
CTD	decreases(expression)			SLC30A5		C025589
CTD	affects(cotreatment)			SLC30A6		C025589
CTD	decreases(expression)			SLC30A6		C025589
CTD	affects(cotreatment)			SLC30A7		C025589
CTD	decreases(expression)			SLC30A7		C025589
CTD	increases(reaction)			SLC30A7		C025589
CTD	decreases(expression)			SLC39A1		C025589
CTD	increases(reaction)			SLC39A1		C025589
CTD	affects(cotreatment)			SLC39A10		C025589
CTD	decreases(expression)			SLC39A10		C025589
CTD	affects(cotreatment)			SLC39A14		C025589
CTD	decreases(expression)			SLC39A14		C025589
CTD	decreases(expression)			SLC39A7		C025589
CTD	decreases(expression)			SLC39A9		C025589
CTD	decreases(expression)			SLC43A1		C025589
CTD	affects(expression)			SLC7A11		C025589
CTD	increases(expression)			SOD1		C025589
CTD	increases(expression)			SOD2		C025589
CTD	increases(expression)			SOD3		C025589
CTD	increases(expression)			SORD		C025589
CTD	decreases(expression)			SOS2		C025589
CTD	decreases(expression)			SPATA7		C025589
CTD	increases(expression)			SPATS2L		C025589
CTD	decreases(expression)			SPTBN1		C025589
CTD	decreases(expression)			STAM2		C025589
CTD	decreases(expression)			STAM2		C025589
CTD	increases(expression)			STC1		C025589
CTD	decreases(expression)			STX7		C025589
CTD	decreases(expression)			TARDBP		C025589
CTD	decreases(expression)			TMCO6		C025589
CTD	decreases(expression)			TMEM177		C025589
CTD	decreases(expression)			TMEM37		C025589
CTD	decreases(expression)			TMEM50B		C025589
CTD	decreases(reaction)			TNF		C025589
CTD	increases(expression)			TNF		C025589
CTD	decreases(expression)			TNFRSF1A		C025589
CTD	increases(expression)			TP53		C025589
CTD	increases(expression)			TPM3		C025589
CTD	decreases(expression)			TRAK1		C025589
CTD	decreases(expression)			TRIM24		C025589
CTD	decreases(expression)			TRRAP		C025589
CTD	decreases(expression)			TUBB1		C025589
CTD	increases(expression)			TXN2		C025589
CTD	decreases(expression)			UCP1		C025589
CTD	decreases(expression)			UCP2		C025589
CTD	increases(expression)			UCP2		C025589
CTD	increases(expression)			UCP3		C025589
CTD	increases(expression)			UGT1A6		C025589
CTD	decreases(expression)			UPF3B		C025589
CTD	increases(expression)			UQCR11		C025589
CTD	increases(expression)			UQCRH		C025589
CTD	increases(expression)			UQCRQ		C025589
CTD	decreases(expression)			VEGFA		C025589
CTD	decreases(reaction)			VEGFA		C025589
CTD	decreases(expression)			VLDLR		C025589
CTD	decreases(expression)			WDR33		C025589
CTD	decreases(expression)			XAF1		C025589
CTD	increases(expression)			XDH		C025589
CTD	decreases(expression)			ZNF628		C025589
CTD	decreases(expression)			ZNF652		C025589
PubChem	Potency	uM	44.668	ESR1	-	GI(Protien) :
PubChem	Potency	uM	44.668	NFKB1	-	GI(Protien) :
PubChem	Potency	uM	44.668	NR1H4	-	GI(Protien) :
PubChem	Potency	uM	0.891	NR3C1	-	GI(Protien) :
PubChem	Potency	uM	39.811	PPARD	-	GI(Protien) :
PubChem	Potency	uM	1.995	PPARG	-	GI(Protien) :
PubChem	Potency	uM	44.668	THRB	-	GI(Protien) :
PubChem	Potency	uM	44.668	VDR	-	GI(Protien) :

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