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Gene Set: D4 : CTD - 2-hydroxyestrone

Collection D4 : CTD
Chemical Name 2-hydroxyestrone ( From PubChem : 1,3,5[10]-ESTRATRIENE-2,3-DIOL-17-ONE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
286.365 g/mol 2 3 3.523 True
Structure
InChI InChI=1S/C18H22O3/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-15(19)16(20)9-13(10)11/h8-9,11-12,14,19-20H,2-7H2,1H3/t11-,12-,14+,18-/m0/s1
InChIKey SWINWPBPEKHUOD-LFPKGMGHSA-N
Links

Gene (11 / 14)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDaffects(binding)ESR1
C024980
CTDincreases(activity)ESR1
C024980
CTDaffects(binding)ESR1
C024980
CTDaffects(binding)ESR2
C024980
CTDincreases(activity)ESR2
C024980
CTDdecreases(expression)FSHB
C024980
CTDdecreases(expression)LHB
C024980
CTDincreases(glucuronidation)UGT1A1
C024980
CTDincreases(glucuronidation)UGT1A10
C024980
CTDincreases(glucuronidation)UGT1A3
C024980
CTDincreases(glucuronidation)UGT1A7
C024980
CTDincreases(glucuronidation)UGT1A8
C024980
CTDincreases(glucuronidation)UGT1A9
C024980
CTDincreases(metabolic processing)UGT2B15
C024980
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