Tan Lab | DSigDB

Gene Set: D4 : CTD - taxifolin

Collection

D4 : CTD

Chemical Name

taxifolin ( From PubChem : TAXIFOLIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
304.252 g/mol	5	7	1.1863	True

Structure

InChI

InChI=1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15+/m0/s1

InChIKey

CXQWRCVTCMQVQX-LSDHHAIUSA-N

Links

Gene (36 / 52)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(export)			ABCC1		C003377
CTD	decreases(reaction)			ABCC1		C003377
CTD	decreases(activity)			ABCC1		C003377
CTD	increases(expression)			APOA1		C003377
CTD	decreases(expression)			APOB		C003377
CTD	decreases(secretion)			APOB		C003377
CTD	decreases(expression)			CCNA1		C003377
CTD	decreases(expression)			CDC25A		C003377
CTD	decreases(expression)			CYP2E1		C003377
CTD	increases(expression)			DCC		C003377
CTD	decreases(expression)			EGF		C003377
CTD	decreases(expression)			FGF18		C003377
CTD	decreases(expression)			FGF3		C003377
CTD	increases(expression)			GAS6		C003377
CTD	increases(expression)			GDF15		C003377
CTD	increases(expression)			GSTM1		C003377
CTD	increases(expression)			HMOX1		C003377
CTD	decreases(reaction)			ICAM1		C003377
CTD	increases(expression)			ICAM1		C003377
CTD	decreases(reaction)			IFNG		C003377
CTD	increases(activity)			IFNG		C003377
CTD	increases(localization)			IFNG		C003377
CTD	decreases(reaction)			IFNG		C003377
CTD	increases(expression)			IFNG		C003377
CTD	increases(phosphorylation)			IFNG		C003377
CTD	decreases(expression)			JUN		C003377
CTD	decreases(reaction)			MAPK8		C003377
CTD	increases(phosphorylation)			MAPK8		C003377
CTD	decreases(activity)			MTTP		C003377
CTD	increases(expression)			NFE2L2		C003377
CTD	increases(activity)			NQO1		C003377
CTD	increases(expression)			NQO1		C003377
CTD	decreases(expression)			PDGFB		C003377
CTD	decreases(expression)			RASA1		C003377
CTD	decreases(reaction)			STAT1		C003377
CTD	increases(activity)			STAT1		C003377
CTD	increases(localization)			STAT1		C003377
CTD	increases(expression)			TRAF3		C003377
CTD	increases(expression)			TXNRD1		C003377
CTD	decreases(reaction)			XDH		C003377
CTD	increases(chemical synthesis)			XDH		C003377
CTD	increases(expression)			XPA		C003377
CTD	increases(expression)			XRCC4		C003377
PubChem	Potency	uM	10.000	EHMT2	-	GI(Protien) :
PubChem	None	uM		GFER	-	GI(Protien) :
PubChem	None	uM		LYPLA2	-	GI(Protien) :
PubChem	Potency	uM	3.162	POLB	-	GI(Protien) :
PubChem	Potency	uM	79.433	POLI	-	GI(Protien) :
PubChem	None	uM		PSIP1	-	GI(Protien) :
ChEMBL	Potency	nM	10000.000	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	19952.600	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	3162.300	POLB	-	Target : CHEMBL2392

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