Tan Lab | DSigDB

Gene Set: D4 : CTD - profenofos

Collection

D4 : CTD

Chemical Name

profenofos ( From PubChem : PROFENOFOS )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
373.631 g/mol	0	4	5.7691	False(3/4)

Structure

InChI

InChI=1S/C11H15BrClO3PS/c1-3-7-18-17(14,15-4-2)16-11-6-5-9(12)8-10(11)13/h5-6,8H,3-4,7H2,1-2H3/t17-/m0/s1

InChIKey

Links

Gene (11 / 23)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			CYP1A2		C024273
CTD	increases(expression)			CYP2A6		C024273
CTD	increases(metabolic processing)			CYP2B6		C024273
CTD	increases(abundance)			CYP2B6		C024273
CTD	decreases(activity)			CYP2B6		C024273
CTD	increases(expression)			CYP2B6		C024273
CTD	increases(metabolic processing)			CYP2C19		C024273
CTD	increases(abundance)			CYP2C19		C024273
CTD	decreases(reaction)			CYP2C9		C024273
CTD	increases(hydroxylation)			CYP2C9		C024273
CTD	decreases(activity)			CYP2C9		C024273
CTD	decreases(reaction)			CYP2E1		C024273
CTD	increases(hydroxylation)			CYP2E1		C024273
CTD	decreases(activity)			CYP2E1		C024273
CTD	increases(metabolic processing)			CYP3A4		C024273
CTD	increases(abundance)			CYP3A4		C024273
CTD	increases(activity)			CYP3A4		C024273
CTD	increases(expression)			CYP3A4		C024273
CTD	increases(expression)			NR1I3		C024273
PubChem	AhR Potency (uM)	uM	4.191	AHR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.189	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		ESR1	-	GI(Protien) :

Download gene sets