Tan Lab | DSigDB

Gene Set: D4 : CTD - tiotidine

Collection

D4 : CTD

Chemical Name

tiotidine ( From PubChem : TIOTIDINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
312.418 g/mol	4	10	2.10968	True

Structure

InChI

InChI=1S/C10H16N8S2/c1-14-9(16-6-11)15-2-3-19-4-7-5-20-10(17-7)18-8(12)13/h5H,2-4H2,1H3,(H2,14,15,16)(H4,12,13,17,18)

InChIKey

Links

Gene (5 / 24)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			CD40		C023990
CTD	decreases(expression)			CD40		C023990
CTD	decreases(reaction)			CD40		C023990
CTD	increases(activity)			CD40		C023990
CTD	affects(binding)			HRH2		C023990
CTD	decreases(reaction)			HRH2		C023990
CTD	affects(binding)			HRH2		C023990
CTD	decreases(activity)			HRH2		C023990
CTD	decreases(reaction)			HRH2		C023990
CTD	increases(activity)			HRH2		C023990
CTD	decreases(expression)			HRH2		C023990
CTD	increases(expression)			HRH2		C023990
CTD	affects(binding)			PTPRC		C023990
CTD	decreases(expression)			PTPRC		C023990
CTD	decreases(reaction)			PTPRC		C023990
CTD	increases(activity)			PTPRC		C023990
PubChem	Potency	uM	1.259	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	15.849	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
ChEMBL	AC50	nM	1258.930	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	1258.900	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	15848.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	15848.900	CYP3A4	-	Target : CHEMBL340

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