Tan Lab | DSigDB

Gene Set: D4 : CTD - triciribine

Collection

D4 : CTD

Chemical Name

triciribine ( From PubChem : TRICIRIBINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
320.304 g/mol	4	10	-0.9071	True

Structure

InChI

InChI=1S/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/m1/s1

InChIKey

HOGVTUZUJGHKPL-HTVVRFAVSA-N

Links

Gene (11 / 17)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(phosphorylation)			AKT1		C023764
CTD	decreases(phosphorylation)			AKT2		C023764
CTD	affects(localization)			BAX		C023764
CTD	decreases(reaction)			BAX		C023764
CTD	decreases(activity)			FSHB		C023764
PubChem	Potency-Replicate_1	uM	13.333	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	18.125	AHR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	0.511	AR	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	6.944	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	7.498	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	6.430	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	10.590	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	2.593	TDP1	-	GI(Protien) :
PubChem	Potency	uM	10.593	TDP1	-	GI(Protien) :

Download gene sets

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