Tan Lab | DSigDB

Gene Set: D4 : CTD - benzo(k)fluoranthene

Collection

D4 : CTD

Chemical Name

benzo(k)fluoranthene ( From PubChem : BENZO[K]FLUORANTHENE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
252.309 g/mol	0	0	5.6404	False(3/4)

Structure

InChI

InChI=1S/C20H12/c1-2-6-15-12-19-17-10-4-8-13-7-3-9-16(20(13)17)18(19)11-14(15)5-1/h1-12H

InChIKey

HAXBIWFMXWRORI-UHFFFAOYSA-N

Links

Gene (74 / 157)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCB1		C022921
CTD	increases(expression)			ABCG2		C022921
CTD	increases(reaction)			ABCG2		C022921
CTD	increases(reaction)			ABCG2		C022921
CTD	increases(transport)			ABCG2		C022921
CTD	increases(expression)			ABCG2		C022921
CTD	increases(activity)			ABCG2		C022921
CTD	increases(expression)			AHR		C022921
CTD	increases(reaction)			AHR		C022921
CTD	affects(binding)			AHR		C022921
CTD	decreases(reaction)			AHR		C022921
CTD	increases(activity)			AHR		C022921
CTD	increases(expression)			AHR		C022921
CTD	affects(cotreatment)			AHR		C022921
CTD	increases(activity)			AHR		C022921
CTD	increases(reaction)			AHR		C022921
CTD	affects(binding)			AHR		C022921
CTD	increases(activity)			AHR		C022921
CTD	increases(expression)			AHR		C022921
CTD	increases(reaction)			AHR		C022921
CTD	increases(expression)			AKR1C1		C022921
CTD	decreases(expression)			AKT2		C022921
CTD	decreases(reaction)			AR		C022921
CTD	increases(activity)			AR		C022921
CTD	decreases(activity)			AR		C022921
CTD	decreases(expression)			CADM1		C022921
CTD	increases(expression)			CBR3		C022921
CTD	decreases(expression)			CELSR2		C022921
CTD	decreases(expression)			CLDN17		C022921
CTD	decreases(expression)			COL2A1		C022921
CTD	decreases(expression)			COL4A6		C022921
CTD	decreases(expression)			CXCL8		C022921
CTD	affects(binding)			CYP1A1		C022921
CTD	decreases(reaction)			CYP1A1		C022921
CTD	increases(activity)			CYP1A1		C022921
CTD	increases(expression)			CYP1A1		C022921
CTD	affects(reaction)			CYP1A1		C022921
CTD	increases(hydroxylation)			CYP1A1		C022921
CTD	increases(expression)			CYP1A1		C022921
CTD	increases(expression)			CYP1A1		C022921
CTD	increases(reaction)			CYP1A1		C022921
CTD	increases(activity)			CYP1A1		C022921
CTD	increases(expression)			CYP1A1		C022921
CTD	increases(expression)			CYP1A1		C022921
CTD	decreases(reaction)			CYP1A1		C022921
CTD	increases(activity)			CYP1A1		C022921
CTD	decreases(reaction)			CYP1A1		C022921
CTD	increases(expression)			CYP1A1		C022921
CTD	affects(reaction)			CYP1A1		C022921
CTD	decreases(reaction)			CYP1A1		C022921
CTD	increases(activity)			CYP1A1		C022921
CTD	increases(expression)			CYP1A1		C022921
CTD	decreases(reaction)			CYP1A1		C022921
CTD	increases(expression)			CYP1A1		C022921
CTD	increases(expression)			CYP1A1		C022921
CTD	increases(reaction)			CYP1A1		C022921
CTD	affects(cotreatment)			CYP1A1		C022921
CTD	increases(expression)			CYP1A1		C022921
CTD	decreases(reaction)			CYP1A1		C022921
CTD	increases(activity)			CYP1A1		C022921
CTD	decreases(reaction)			CYP1A1		C022921
CTD	increases(expression)			CYP1A1		C022921
CTD	decreases(reaction)			CYP1A1		C022921
CTD	increases(expression)			CYP1A1		C022921
CTD	decreases(activity)			CYP1A2		C022921
CTD	increases(expression)			CYP1A2		C022921
CTD	increases(expression)			CYP1A2		C022921
CTD	decreases(reaction)			CYP1A2		C022921
CTD	increases(expression)			CYP1A2		C022921
CTD	affects(reaction)			CYP1B1		C022921
CTD	increases(hydroxylation)			CYP1B1		C022921
CTD	increases(expression)			CYP1B1		C022921
CTD	affects(cotreatment)			CYP1B1		C022921
CTD	increases(expression)			CYP1B1		C022921
CTD	decreases(expression)			ERBB2		C022921
CTD	decreases(reaction)			ETS1		C022921
CTD	increases(expression)			ETS1		C022921
CTD	increases(expression)			FGF9		C022921
CTD	decreases(expression)			FLNB		C022921
CTD	increases(expression)			FOS		C022921
CTD	decreases(expression)			FREM1		C022921
CTD	decreases(expression)			GSTM1		C022921
CTD	increases(activity)			HIF1A		C022921
CTD	affects(reaction)			HMOX1		C022921
CTD	decreases(reaction)			HMOX1		C022921
CTD	increases(activity)			HMOX1		C022921
CTD	increases(expression)			HMOX1		C022921
CTD	increases(expression)			IER3		C022921
CTD	decreases(reaction)			ITGA2		C022921
CTD	increases(expression)			ITGA2		C022921
CTD	decreases(reaction)			JUN		C022921
CTD	increases(expression)			JUN		C022921
CTD	increases(expression)			JUN		C022921
CTD	decreases(expression)			KHK		C022921
CTD	decreases(reaction)			KLK3		C022921
CTD	increases(expression)			KLK3		C022921
CTD	increases(reaction)			KLK3		C022921
CTD	increases(expression)			LGALS1		C022921
CTD	decreases(reaction)			MAPK14		C022921
CTD	increases(phosphorylation)			MAPK14		C022921
CTD	increases(expression)			MIR1180		C022921
CTD	increases(expression)			MIR1275		C022921
CTD	increases(expression)			MIR1301		C022921
CTD	increases(expression)			MIR181D		C022921
CTD	increases(expression)			MIR198		C022921
CTD	increases(expression)			MIR200C		C022921
CTD	increases(expression)			MIR22		C022921
CTD	increases(expression)			MIR221		C022921
CTD	increases(expression)			MIR23B		C022921
CTD	decreases(expression)			MIR33A		C022921
CTD	increases(expression)			MIR629		C022921
CTD	increases(expression)			MIR658		C022921
CTD	increases(expression)			MIRLET7B		C022921
CTD	decreases(reaction)			MMP1		C022921
CTD	increases(expression)			MMP1		C022921
CTD	decreases(reaction)			MMP25		C022921
CTD	increases(expression)			MMP25		C022921
CTD	decreases(expression)			MYLK		C022921
CTD	decreases(expression)			NDC80		C022921
CTD	increases(expression)			NQO1		C022921
CTD	decreases(expression)			PAH		C022921
CTD	increases(cleavage)			PARP1		C022921
CTD	decreases(expression)			PCDHGA8		C022921
CTD	decreases(expression)			PKD1		C022921
CTD	decreases(expression)			RELN		C022921
CTD	increases(expression)			RHOC		C022921
CTD	decreases(expression)			SHC3		C022921
CTD	decreases(reaction)			SNAI1		C022921
CTD	increases(expression)			SNAI1		C022921
CTD	decreases(response to substance)			SPTLC1		C022921
CTD	increases(expression)			TIMP1		C022921
CTD	increases(expression)			TIPARP		C022921
CTD	decreases(expression)			TLN2		C022921
CTD	increases(expression)			UGT1A6		C022921
CTD	affects(cotreatment)			UGT1A6		C022921
CTD	affects(cotreatment)			UGT1A7		C022921
CTD	increases(expression)			UGT1A7		C022921
CTD	decreases(expression)			VAV3		C022921
PubChem	AhR Potency (uM)	uM	0.038	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.120	AHR	-	GI(Protien) :
PubChem	Potency	uM	2.512	AHR	-	GI(Protien) :
PubChem	Potency	uM	2.818	AHR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	1.202	AR	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	0.198	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.269	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.922	HSPB1	-	GI(Protien) :
PubChem	Potency	uM	1.883	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	1.933	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	8.635	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	9.439	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	4.467	NFKB1	-	GI(Protien) :
PubChem	Potency	uM	7.080	NFKB1	-	GI(Protien) :
PubChem	Potency	uM	3.162	NR1H4	-	GI(Protien) :
PubChem	Potency	uM	15.849	NR3C1	-	GI(Protien) :
PubChem	Potency	uM	2.818	RXRA	-	GI(Protien) :
PubChem	Potency	uM	7.943	THRB	-	GI(Protien) :
ChEMBL	Potency	nM	39810.700	HSD17B10	-	Target : CHEMBL4159

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