Tan Lab | DSigDB

Gene Set: D4 : CTD - phosalone

Collection

D4 : CTD

Chemical Name

phosalone ( From PubChem : PHOSALONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
367.809 g/mol	0	7	4.8867	True

Structure

InChI

InChI=1S/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3

InChIKey

Links

Gene (11 / 27)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			ABCB1		C003117
CTD	increases(reaction)			ABCB1		C003117
CTD	increases(transport)			ABCB1		C003117
CTD	decreases(activity)			ABCB1		C003117
CTD	affects(cotreatment)			ABCB1		C003117
CTD	decreases(reaction)			AR		C003117
CTD	increases(activity)			AR		C003117
CTD	affects(binding)			NR1I2		C003117
CTD	increases(activity)			NR1I2		C003117
CTD	increases(activity)			NR1I3		C003117
CTD	increases(activity)			RARA		C003117
PubChem	Potency-Replicate_1	uM	32.863	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	32.863	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	33.082	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.131	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	65.570	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	65.570	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	0.794	CYP3A4	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	54.941	HSPB1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	9.688	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	10.068	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	26.104	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	27.306	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	10.000	NR1I2	-	GI(Protien) :
PubChem	Potency	uM	35.481	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	794.300	CYP3A4	-	Target : CHEMBL340

Download gene sets