DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : CTD - tetrabromobisphenol A

Collection D4 : CTD
Chemical Name tetrabromobisphenol A ( From PubChem : TETRABROMOBISPHENOL A )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
543.871 g/mol 2 2 6.4737 False(2/4)
Structure
InChI InChI=1S/C15H12Br4O2/c1-15(2,7-3-9(16)13(20)10(17)4-7)8-5-11(18)14(21)12(19)6-8/h3-6,20-21H,1-2H3
InChIKey VEORPZCZECFIRK-UHFFFAOYSA-N
Links

Gene (42 / 128)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(activity)ABCB1
C020806
CTDdecreases(activity)ABCC1
C020806
CTDdecreases(activity)ABCC4
C020806
CTDdecreases(activity)ABCG2
C020806
CTDincreases(secretion)APP
C020806
CTDaffects(binding)AR
C020806
CTDdecreases(activity)AR
C020806
CTDaffects(binding)AR
C020806
CTDdecreases(reaction)AR
C020806
CTDincreases(activity)AR
C020806
CTDdecreases(reaction)AR
C020806
CTDincreases(activity)AR
C020806
CTDincreases(activity)CASP3
C020806
CTDincreases(activity)CASP7
C020806
CTDaffects(binding)CHRNA4
C020806
CTDdecreases(reaction)CHRNA4
C020806
CTDincreases(activity)CHRNA4
C020806
CTDaffects(cotreatment)CHRNA4
C020806
CTDdecreases(reaction)CHRNA4
C020806
CTDincreases(activity)CHRNA4
C020806
CTDaffects(binding)CHRNB2
C020806
CTDdecreases(reaction)CHRNB2
C020806
CTDincreases(activity)CHRNB2
C020806
CTDaffects(cotreatment)CHRNB2
C020806
CTDdecreases(reaction)CHRNB2
C020806
CTDincreases(activity)CHRNB2
C020806
CTDdecreases(activity)CYP19A1
C020806
CTDincreases(expression)CYP21A2
C020806
CTDaffects(binding)ESR1
C020806
CTDincreases(activity)ESR1
C020806
CTDaffects(binding)ESR1
C020806
CTDaffects(binding)GABRA1
C020806
CTDaffects(reaction)GABRA1
C020806
CTDincreases(activity)GABRA1
C020806
CTDincreases(reaction)GABRA1
C020806
CTDaffects(binding)GABRB2
C020806
CTDaffects(reaction)GABRB2
C020806
CTDincreases(activity)GABRB2
C020806
CTDincreases(reaction)GABRB2
C020806
CTDaffects(binding)GABRG2
C020806
CTDaffects(reaction)GABRG2
C020806
CTDincreases(activity)GABRG2
C020806
CTDincreases(reaction)GABRG2
C020806
CTDdecreases(phosphorylation)MAPK1
C020806
CTDincreases(phosphorylation)MAPK1
C020806
CTDdecreases(reaction)MAPK1
C020806
CTDdecreases(reaction)MAPK1
C020806
CTDincreases(phosphorylation)MAPK1
C020806
CTDdecreases(phosphorylation)MAPK3
C020806
CTDincreases(phosphorylation)MAPK3
C020806
CTDdecreases(reaction)MAPK3
C020806
CTDdecreases(reaction)MAPK3
C020806
CTDincreases(phosphorylation)MAPK3
C020806
CTDaffects(binding)NR1I2
C020806
CTDincreases(activity)NR1I2
C020806
CTDaffects(binding)PGR
C020806
CTDdecreases(activity)PGR
C020806
CTDincreases(expression)PGR
C020806
CTDaffects(binding)PPARG
C020806
CTDincreases(activity)PPARG
C020806
CTDaffects(binding)PPARG
C020806
CTDincreases(activity)PPARG
C020806
CTDincreases(activity)PPARG
C020806
CTDaffects(binding)SERPINA7
C020806
CTDdecreases(reaction)SERPINA7
C020806
CTDaffects(cotreatment)SULT1A1
C020806
CTDdecreases(reaction)SULT1A1
C020806
CTDincreases(activity)SULT1A1
C020806
CTDaffects(binding)SULT1E1
C020806
CTDaffects(cotreatment)SULT1E1
C020806
CTDdecreases(reaction)SULT1E1
C020806
CTDdecreases(activity)SULT1E1
C020806
CTDincreases(expression)TFF1
C020806
CTDaffects(activity)THRA
C020806
CTDaffects(binding)THRA
C020806
CTDincreases(activity)THRA
C020806
CTDdecreases(reaction)THRA
C020806
CTDdecreases(reaction)THRA
C020806
CTDincreases(activity)THRA
C020806
CTDdecreases(reaction)THRB
C020806
CTDincreases(activity)THRB
C020806
CTDaffects(binding)TTR
C020806
CTDaffects(binding)TTR
C020806
CTDdecreases(reaction)TTR
C020806
PubChem PotencyuM2.512ALOX15-GI(Protien) :
PubChem PotencyuM15.849ALOX15-GI(Protien) :
PubChem Potency-Replicate_1uM43.497AR-GI(Protien) :
PubChem Potency-Replicate_1uM46.336AR-GI(Protien) :
PubChem AR Potency (uM)uM71.056AR-GI(Protien) :
PubChem PotencyuM56.234BAZ2B-GI(Protien) :
PubChem Potency-Replicate_1uM57.851CYP19A1-GI(Protien) :
PubChem Potency-Replicate_1uM60.882CYP19A1-GI(Protien) :
PubChem NoneuMCYP19A1-GI(Protien) :
PubChem PotencyuM15.849CYP3A4-GI(Protien) :
PubChem NoneuMDRD3-GI(Protien) :
PubChem NoneuMDRD3-GI(Protien) :
PubChem PotencyuM25.119ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM43.492ESR1-GI(Protien) :
PubChem PotencyuM44.668ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM54.760ESR1-GI(Protien) :
PubChem NoneuMFGF22-GI(Protien) :
PubChem Ratio Potency (uM)uM54.760HSPB1-GI(Protien) :
PubChem Ratio Potency (uM)uM15.293NFE2L2-GI(Protien) :
PubChem Ratio Potency (uM)uM21.742NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM23.031NFE2L2-GI(Protien) :
PubChem PotencyuM23.710NFE2L2-GI(Protien) :
PubChem PotencyuM29.849NFE2L2-GI(Protien) :
PubChem PotencyuM48.558NFE2L2-GI(Protien) :
PubChem NoneuMNLRP3-GI(Protien) :
PubChem NoneuMNLRP3-GI(Protien) :
PubChem PotencyuM28.184NR1H4-GI(Protien) :
PubChem NoneuMNR1H4-GI(Protien) :
PubChem PotencyuM44.668NR3C1-GI(Protien) :
PubChem NoneuMNR3C1-GI(Protien) :
PubChem PotencyuM26.680PLK1-GI(Protien) :
PubChem Ratio Potency (uM)uM1.459PPARG-GI(Protien) :
PubChem Potency-Replicate_1uM1.945PPARG-GI(Protien) :
PubChem PotencyuM35.481PPARG-GI(Protien) :
PubChem NoneuMPPARG-GI(Protien) :
ChEMBLPotencynM2511.900ALOX15
-Target : CHEMBL2903
ChEMBLPotencynM15848.900ALOX15
-Target : CHEMBL2903
ChEMBLPotencynM56234.100BAZ2B
-Target : CHEMBL1741220
ChEMBLPotencynM15848.900CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM3981.100HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM10000.000HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM15848.900HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM89125.100KDM4A
-Target : CHEMBL5896
ChEMBLPotencynM22387.200RECQL
-Target : CHEMBL1293236
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).