Tan Lab | DSigDB

Gene Set: D4 : CTD - herbimycin

Collection

D4 : CTD

Chemical Name

herbimycin ( From PubChem : HERBIMYCIN A )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
574.662 g/mol	2	11	3.7424	False(2/4)

Structure

InChI

InChI=1S/C30H42N2O9/c1-16-10-9-11-23(37-5)28(41-30(31)36)18(3)12-17(2)27(40-8)24(38-6)13-19(4)26(39-7)21-14-20(33)15-22(25(21)34)32-29(16)35/h9-12,14-15,17,19,23-24,26-28H,13H2,1-8H3,(H2,31,36)(H,32,35)

InChIKey

MCAHMSDENAOJFZ-UHFFFAOYSA-N

Links

Gene (13 / 27)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
CTD	decreases(reaction)		ACE		C020754
CTD	increases(expression)		ACE		C020754
CTD	decreases(expression)		AHR		C020754
CTD	decreases(reaction)		AHR		C020754
CTD	increases(activity)		CACNA1H		C020754
CTD	decreases(reaction)		CYP1A1		C020754
CTD	increases(expression)		CYP1A1		C020754
CTD	decreases(reaction)		HMOX1		C020754
CTD	increases(expression)		HMOX1		C020754
CTD	decreases(reaction)		ICAM1		C020754
CTD	increases(expression)		ICAM1		C020754
CTD	decreases(reaction)		IFNG		C020754
CTD	increases(expression)		IFNG		C020754
CTD	affects(localization)		MAPK1		C020754
CTD	decreases(reaction)		MAPK1		C020754
CTD	increases(phosphorylation)		MAPK1		C020754
CTD	decreases(reaction)		MMP1		C020754
CTD	increases(expression)		MMP1		C020754
CTD	decreases(reaction)		TIMP1		C020754
CTD	increases(expression)		TIMP1		C020754
CTD	decreases(reaction)		TNF		C020754
CTD	increases(expression)		TNF		C020754
CTD	decreases(reaction)		TNF		C020754
CTD	increases(expression)		TNF		C020754
CTD	decreases(reaction)		VEGFA		C020754
CTD	increases(expression)		VEGFA		C020754
ChEMBL	Activity	-	HSP90AA1	-	Target : CHEMBL3880

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