Tan Lab | DSigDB

Gene Set: D4 : CTD - dibutyldichlorotin

Collection

D4 : CTD

Chemical Name

dibutyldichlorotin ( From PubChem : DIBUTYLTIN DICHLORIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
303.836 g/mol	0	0	4.5064	True

Structure

InChI

InChI=1S/2C4H9.2ClH.Sn/c2*1-3-4-2;;;/h2*1,3-4H2,2H3;2*1H;/q;;;;+2/p-2

InChIKey

RJGHQTVXGKYATR-UHFFFAOYSA-L

Links

Gene (20 / 39)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			CD84		C020735
CTD	decreases(activity)			CYP19A1		C020735
CTD	increases(expression)			DNAJB1		C020735
CTD	increases(expression)			DNAJB4		C020735
CTD	increases(activity)			HSD17B1		C020735
CTD	increases(expression)			HSPA1B		C020735
CTD	increases(expression)			HSPA6		C020735
CTD	increases(expression)			HSPH1		C020735
CTD	increases(expression)			SLC7A11		C020735
CTD	decreases(activity)			SRD5A1		C020735
CTD	decreases(activity)			SRD5A2		C020735
CTD	increases(expression)			ZBED8		C020735
PubChem	Ratio Potency (uM)	uM	0.030	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.095	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	0.132	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.217	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	0.276	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.390	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.172	CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.694	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.018	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.157	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.692	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.786	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	33.143	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	34.674	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	43.641	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	44.208	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	15.485	HSPB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.031	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	1.933	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	15.849	NR3C1	-	GI(Protien) :
PubChem	Potency	uM	3.981	PPARD	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	5.494	PPARD	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	13.980	PPARD	-	GI(Protien) :
PubChem	None	uM		PPARD	-	GI(Protien) :
PubChem	Potency	uM	3.981	RXRA	-	GI(Protien) :
PubChem	None	uM		VDR	-	GI(Protien) :

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