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Gene Set: D4 : Boss - frangula emodin

Collection D4 : Boss
Chemical Name frangula emodin ( From PubChem : EMODIN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
270.237 g/mol 3 5 1.8872 True
Structure
InChI InChI=1S/C15H10O5/c1-6-2-8-12(10(17)3-6)15(20)13-9(14(8)19)4-7(16)5-11(13)18/h2-5,16-18H,1H3
InChIKey RHMXXJGYXNZAPX-UHFFFAOYSA-N
Links

Gene (62 / 110)


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Source Type Unit Value Gene PMID Assay Other
BOSSText MiningABCA1
BOSSText MiningATP8A2
BOSSText MiningBBS9
BOSSText MiningBCL2
BOSSText MiningCASP3
BOSSText MiningCASP9
BOSSText MiningCDT1
BOSSText MiningCYCS
BOSSText MiningDDR2
BOSSText MiningELF3
BOSSText MiningERCC1
BOSSText MiningGPR182
BOSSText MiningGYPE
BOSSText MiningIL10
BOSSText MiningIL1B
BOSSText MiningIL6
BOSSText MiningIRF6
BOSSText MiningMAPK3
BOSSText MiningMMP2
BOSSText MiningMMP9
BOSSText MiningMPO
BOSSText MiningNSG1
BOSSText MiningROS1
BOSSText MiningSLC7A1
BOSSText MiningSOD1
BOSSText MiningTAOK1
BOSSText MiningTNF
BOSSText MiningTP53
PubChem Potency-Replicate_1uM5.974AHR-GI(Protien) :
PubChem AhR Potency (uM)uM8.438AHR-GI(Protien) :
PubChem AhR Potency (uM)uM14.221AHR-GI(Protien) :
PubChem Potency-Replicate_1uM34.376AHR-GI(Protien) :
PubChem PotencyuM44.668AHR-GI(Protien) :
PubChem PotencyuM12.589ALDH1A1-GI(Protien) :
PubChem PotencyuM14.125ALDH1A1-GI(Protien) :
PubChem PotencyuM22.387ALDH1A1-GI(Protien) :
PubChem Potency-Replicate_1uM26.918AR-GI(Protien) :
PubChem NoneuMCASP3-GI(Protien) :
PubChem PotencyuM22.387CBX1-GI(Protien) :
PubChem PotencyuM66.824CXCL8-GI(Protien) :
PubChem Potency-Replicate_1uM23.782CYP19A1-GI(Protien) :
PubChem Potency-Replicate_1uM54.483CYP19A1-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM7.943CYP2C19-GI(Protien) :
PubChem PotencyuM3.981CYP2C9-GI(Protien) :
PubChem PotencyuM7.943CYP2C9-GI(Protien) :
PubChem PotencyuM12.589CYP2D6-GI(Protien) :
PubChem PotencyuM31.623CYP2D6-GI(Protien) :
PubChem PotencyuM10.000CYP3A4-GI(Protien) :
PubChem PotencyuM1.683EHMT2-GI(Protien) :
PubChem PotencyuM8.912EHMT2-GI(Protien) :
PubChem Potency-Replicate_1uM1.723ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM5.324ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM6.026ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM7.592ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM7.762ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM10.965ESR1-GI(Protien) :
PubChem PotencyuM15.003FEN1-GI(Protien) :
PubChem PotencyuM39.811FEN1-GI(Protien) :
PubChem NoneuMKCNQ1-GI(Protien) :
PubChem PotencyuM8.912MAPT-GI(Protien) :
PubChem PotencyuM10.000MAPT-GI(Protien) :
PubChem NoneuMMAPT-GI(Protien) :
PubChem PotencyuM10.621MPHOSPH8-GI(Protien) :
PubChem Potency-Replicate_1uM4.229NFE2L2-GI(Protien) :
PubChem PotencyuM9.688NFE2L2-GI(Protien) :
PubChem Ratio Potency (uM)uM10.461NFE2L2-GI(Protien) :
PubChem PotencyuM18.834NFE2L2-GI(Protien) :
PubChem NoneuMNR1H4-GI(Protien) :
PubChem NoneuMNR3C1-GI(Protien) :
PubChem NoneuMPIM1-GI(Protien) :
PubChem NoneuMPIM2-GI(Protien) :
PubChem NoneuMPLA2G7-GI(Protien) :
PubChem PotencyuM11.220POLB-GI(Protien) :
PubChem NoneuMPPARG-GI(Protien) :
PubChem NoneuMSENP6-GI(Protien) :
PubChem NoneuMSENP6-GI(Protien) :
PubChem NoneuMSENP7-GI(Protien) :
PubChem NoneuMSENP7-GI(Protien) :
PubChem NoneuMSENP8-GI(Protien) :
PubChem NoneuMSENP8-GI(Protien) :
PubChem NoneuMSENP8-GI(Protien) :
PubChem PotencyuM18.356TDP1-GI(Protien) :
PubChem PotencyuM21.136TDP1-GI(Protien) :
PubChem PotencyuM12.589THPO-GI(Protien) :
ChEMBLPotencynM12589.300ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM22387.200ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM14125.400ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM35481.300APEX1
-Target : CHEMBL5619
ChEMBLPotencynM22387.200CBX1
-Target : CHEMBL1741193
ChEMBLPotencynM7943.300CYP2C19
-Target : CHEMBL3622
ChEMBLPotencynM3981.100CYP2C9
-Target : CHEMBL3397
ChEMBLPotencynM7943.300CYP2C9
-Target : CHEMBL3397
ChEMBLPotencynM31622.800CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM12589.300CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM10000.000CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM8912.500EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM1683.400EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM15003.000FEN1
-Target : CHEMBL5027
ChEMBLPotencynM44668.400KDM4A
-Target : CHEMBL5896
ChEMBLPotencynM8912.500MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM15848.900MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM14125.400MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM10000.000MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM10621.300MPHOSPH8
-Target : CHEMBL1741210
ChEMBLInhibition-PIK3CA
-Target : CHEMBL4005
ChEMBLInhibition-PIK3CA
-Target : CHEMBL4005
ChEMBLPotencynM11220.200POLB
-Target : CHEMBL2392
ChEMBLInhibition-PTP4A3
-Target : CHEMBL4162
ChEMBLPotencynM12589.300THPO
-Target : CHEMBL1293256
Download gene sets gmt, text, Detailed text
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