Tan Lab | DSigDB

Gene Set: D4 : Boss - femera

Collection

D4 : Boss

Chemical Name

femera ( From PubChem : LETROZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Approved	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
285.303 g/mol	0	5	2.65916	True

Structure

InChI

InChI=1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H

InChIKey

Links

Gene (20 / 27)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			AKR1B1
BOSS	Text Mining			BRD2
BOSS	Text Mining			CYP2B6
BOSS	Text Mining			CYP2C8
BOSS	Text Mining			DDR2
BOSS	Text Mining			EGF
BOSS	Text Mining			EGFR
BOSS	Text Mining			ERBB2
BOSS	Text Mining			ERBB2
BOSS	Text Mining			EREG
BOSS	Text Mining			ESR1
BOSS	Text Mining			INS
BOSS	Text Mining			MTOR
BOSS	Text Mining			NR4A1
BOSS	Text Mining			PGR
BOSS	Text Mining			PR@
BOSS	Text Mining			PRL
BOSS	Text Mining			SCN5A
PubChem	Potency-Replicate_1	uM	0.009	CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.014	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	5.012	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
ChEMBL	Inhibition	-		CYP19A1	-	Target : CHEMBL1978
ChEMBL	AC50	nM	5011.870	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	5011.900	CYP3A4	-	Target : CHEMBL340

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