DSigDB

Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

Home

Search Gene

Collection

Browse

Download

Help

DSigDB Home

Search Gene

Collections

Browse Gene Sets

Download

Help

Gene Set: D4 : Boss - docetaxel anhydrous

---

Collection	D4 : Boss
Chemical Name	docetaxel anhydrous ( From PubChem : DOCETAXEL )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Approved Not Approved Approved Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 807.879 g/mol 5 15 3.6505 False(2/4)
Structure
InChI	InChI=1S/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,52)/t26-,27-,28?,30-,31+,32+,33?,35-,41+,42-,43+/m0/s1
InChIKey	ZDZOTLJHXYCWBA-GSQVOXQYSA-N
Links
Gene (142 / 149) ⊖ Less	Source Type Unit Value Gene PMID Assay Other BOSS Text Mining ABCA1 BOSS Text Mining ABCC10 BOSS Text Mining ABCC2 BOSS Text Mining ABCG2 BOSS Text Mining ADAMTS13 BOSS Text Mining AK5 BOSS Text Mining AKR1B1 BOSS Text Mining ALB BOSS Text Mining ALK BOSS Text Mining ATP2C1 BOSS Text Mining ATP8A2 BOSS Text Mining AURKA BOSS Text Mining AURKB BOSS Text Mining AURKC BOSS Text Mining BBS9 BOSS Text Mining BCL2 BOSS Text Mining BCL2L1 BOSS Text Mining BRCA1 BOSS Text Mining C7orf49 BOSS Text Mining CASP3 BOSS Text Mining CASP8 BOSS Text Mining CASP9 BOSS Text Mining CBX8 BOSS Text Mining CCNB1 BOSS Text Mining CD34 BOSS Text Mining CD44 BOSS Text Mining CDCA7L BOSS Text Mining CDH2 BOSS Text Mining CDKN2A BOSS Text Mining CDT1 BOSS Text Mining CEACAM3 BOSS Text Mining CNTN2 BOSS Text Mining COG3 BOSS Text Mining COX8C BOSS Text Mining CREM BOSS Text Mining CSF2 BOSS Text Mining CSF3 BOSS Text Mining CYGB BOSS Text Mining CYLD BOSS Text Mining CYP17A1 BOSS Text Mining CYP2C8 BOSS Text Mining DDR2 BOSS Text Mining DPYS BOSS Text Mining EDN1 BOSS Text Mining EGF BOSS Text Mining EGFR BOSS Text Mining ELF3 BOSS Text Mining EPHB2 BOSS Text Mining ERBB2 BOSS Text Mining ERBB2 BOSS Text Mining ERBB3 BOSS Text Mining ERCC1 BOSS Text Mining EREG BOSS Text Mining ESR1 BOSS Text Mining ETFB BOSS Text Mining FAM3B BOSS Text Mining FLT1 BOSS Text Mining FOXO1 BOSS Text Mining GCK BOSS Text Mining GDF15 BOSS Text Mining GNRH1 BOSS Text Mining HBA1 BOSS Text Mining HBB BOSS Text Mining HIF1A BOSS Text Mining HLP BOSS Text Mining HNF4A BOSS Text Mining HPD BOSS Text Mining HRAS BOSS Text Mining HSPA4 BOSS Text Mining IGFBP1 BOSS Text Mining IGHD1-7 BOSS Text Mining IGLL1 BOSS Text Mining IGLL3P BOSS Text Mining IL3 BOSS Text Mining IL6 BOSS Text Mining KDR BOSS Text Mining KIT BOSS Text Mining KRT5 BOSS Text Mining KRT6B BOSS Text Mining LDHA BOSS Text Mining MAPK3 BOSS Text Mining MCL1 BOSS Text Mining MMP1 BOSS Text Mining MMP2 BOSS Text Mining MMP9 BOSS Text Mining MPP2 BOSS Text Mining MTOR BOSS Text Mining MUC16 BOSS Text Mining MYC BOSS Text Mining NFKB1 BOSS Text Mining NFKB2 BOSS Text Mining NFKBIL1 BOSS Text Mining NLRP1 BOSS Text Mining NR4A1 BOSS Text Mining NSG1 BOSS Text Mining OPTN BOSS Text Mining OXSM BOSS Text Mining PARP2 BOSS Text Mining PCNA BOSS Text Mining PDGFRB BOSS Text Mining PGP BOSS Text Mining PGR BOSS Text Mining PIK3CD BOSS Text Mining PLXNA3 BOSS Text Mining PPARG BOSS Text Mining PPIG BOSS Text Mining PR@ BOSS Text Mining PTEN BOSS Text Mining REG3A BOSS Text Mining RNASEH2A BOSS Text Mining RPN2 BOSS Text Mining SCARNA5 BOSS Text Mining SERPINA1 BOSS Text Mining SERPINB3 BOSS Text Mining SLC22A3 BOSS Text Mining SLC25A16 BOSS Text Mining SLC25A20 BOSS Text Mining SLC52A2 BOSS Text Mining SMUG1 BOSS Text Mining STAT3 BOSS Text Mining TACR2 BOSS Text Mining TAOK1 BOSS Text Mining TENM1 BOSS Text Mining TFE3 BOSS Text Mining THBS1 BOSS Text Mining TIMM8A BOSS Text Mining TNF BOSS Text Mining TNFRSF10B BOSS Text Mining TNFSF10 BOSS Text Mining TP53 BOSS Text Mining TPM3 BOSS Text Mining TRAPPC9 BOSS Text Mining TRPM2 BOSS Text Mining TSC1 BOSS Text Mining TUBB4A BOSS Text Mining TUBB4B BOSS Text Mining TUBE1 BOSS Text Mining TYMS BOSS Text Mining VEGFA BOSS Text Mining VIM PubChem Ratio Potency (uM) uM 0.005 AR - GI(Protien) : PubChem ER Potency (uM) uM 0.060 ESR1 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.060 ESR1 - GI(Protien) : PubChem Potency-Replicate_1 uM 10.682 NR3C1 - GI(Protien) : PubChem None uM NR3C1 - GI(Protien) : PubChem Potency uM 0.001 TDP1 - GI(Protien) : PubChem Potency uM 0.001 TDP1 - GI(Protien) : PubChem Potency uM 0.003 TDP1 - GI(Protien) : PubChem Potency uM 0.003 TDP1 - GI(Protien) :
Download gene sets	gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).