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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : Boss - cyclosporin a from tolypocladium inflatum

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Collection	D4 : Boss
Chemical Name	cyclosporin a from tolypocladium inflatum ( From PubChem : CYCLOSPORIN A )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 1202.61 g/mol 5 23 4.1495 False(2/4)
Structure
InChI	InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)
InChIKey	PMATZTZNYRCHOR-UHFFFAOYSA-N
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Gene (192 / 192) ⊖ Less	Source Type Unit Value Gene PMID Assay Other BOSS Text Mining ABCA1 BOSS Text Mining ABCB11 BOSS Text Mining ABCC2 BOSS Text Mining ABCC3 BOSS Text Mining ABCG2 BOSS Text Mining ABO BOSS Text Mining ACE BOSS Text Mining ADAMTS13 BOSS Text Mining AGT BOSS Text Mining AKR1B1 BOSS Text Mining ALB BOSS Text Mining ANC BOSS Text Mining APP BOSS Text Mining ATF3 BOSS Text Mining ATP1B1 BOSS Text Mining ATP8A2 BOSS Text Mining AURKB BOSS Text Mining B3GAT1 BOSS Text Mining BBS9 BOSS Text Mining BCL2 BOSS Text Mining BCL2L1 BOSS Text Mining BDNF-AS BOSS Text Mining BEST1 BOSS Text Mining C7orf49 BOSS Text Mining CASP3 BOSS Text Mining CASP8 BOSS Text Mining CASP9 BOSS Text Mining CBL BOSS Text Mining CBX8 BOSS Text Mining CCL11 BOSS Text Mining CCL17 BOSS Text Mining CCL5 BOSS Text Mining CCR5 BOSS Text Mining CD28 BOSS Text Mining CD34 BOSS Text Mining CD4 BOSS Text Mining CD55 BOSS Text Mining CD68 BOSS Text Mining CD86 BOSS Text Mining CD8A BOSS Text Mining CDH2 BOSS Text Mining CDT1 BOSS Text Mining CEBPZ BOSS Text Mining CSF2 BOSS Text Mining CSF3 BOSS Text Mining CSH1 BOSS Text Mining CTGF BOSS Text Mining CXXC1 BOSS Text Mining CYCS BOSS Text Mining CYGB BOSS Text Mining CYP2B6 BOSS Text Mining CYP2C8 BOSS Text Mining DDR2 BOSS Text Mining DECR1 BOSS Text Mining DIANPH BOSS Text Mining DLD BOSS Text Mining DNMT1 BOSS Text Mining DNTT BOSS Text Mining DPP4 BOSS Text Mining DSC2 BOSS Text Mining EDN1 BOSS Text Mining EGF BOSS Text Mining EGFR BOSS Text Mining EPHB2 BOSS Text Mining F9 BOSS Text Mining FN1 BOSS Text Mining FOXP3 BOSS Text Mining GFAP BOSS Text Mining GLI2 BOSS Text Mining GPR182 BOSS Text Mining GPX1 BOSS Text Mining GYPE BOSS Text Mining HBB BOSS Text Mining HEBP1 BOSS Text Mining HK1 BOSS Text Mining HLP BOSS Text Mining HMOX1 BOSS Text Mining HPD BOSS Text Mining HSPA5 BOSS Text Mining ICAM1 BOSS Text Mining IDE BOSS Text Mining IFNA1 BOSS Text Mining IFNA17 BOSS Text Mining IFNG BOSS Text Mining IFNL3 BOSS Text Mining IGLL2P BOSS Text Mining IL10 BOSS Text Mining IL13 BOSS Text Mining IL15 BOSS Text Mining IL1B BOSS Text Mining IL2 BOSS Text Mining IL27 BOSS Text Mining IL2RA BOSS Text Mining IL2RB BOSS Text Mining IL3 BOSS Text Mining IL36G BOSS Text Mining IL4 BOSS Text Mining IL5 BOSS Text Mining IL6 BOSS Text Mining INS BOSS Text Mining IRF6 BOSS Text Mining ISYNA1 BOSS Text Mining KRIT1 BOSS Text Mining KRT10 BOSS Text Mining KRT6B BOSS Text Mining LCN1 BOSS Text Mining LCN2 BOSS Text Mining LDHA BOSS Text Mining MAPK3 BOSS Text Mining MMP2 BOSS Text Mining MMP3 BOSS Text Mining MMP9 BOSS Text Mining MMVP1 BOSS Text Mining MPO BOSS Text Mining MTOR BOSS Text Mining MTR BOSS Text Mining MTX1 BOSS Text Mining NANS BOSS Text Mining NDUFA5 BOSS Text Mining NELFCD BOSS Text Mining NFAT5 BOSS Text Mining NFATC1 BOSS Text Mining NFATC2 BOSS Text Mining NFATC3 BOSS Text Mining NFATC4 BOSS Text Mining NFKB1 BOSS Text Mining NFKB2 BOSS Text Mining NFKBIL1 BOSS Text Mining NONO BOSS Text Mining NPHS2 BOSS Text Mining NUP214 BOSS Text Mining OPTN BOSS Text Mining PARP2 BOSS Text Mining PCNA BOSS Text Mining PDE4A BOSS Text Mining PDSS2 BOSS Text Mining PGP BOSS Text Mining PITX1 BOSS Text Mining PLAU BOSS Text Mining PLCB4 BOSS Text Mining PLXNA3 BOSS Text Mining POLD3 BOSS Text Mining POLD4 BOSS Text Mining POMC BOSS Text Mining PPARG BOSS Text Mining PPIA BOSS Text Mining PPIF BOSS Text Mining PPIG BOSS Text Mining PPP1R2 BOSS Text Mining PR@ BOSS Text Mining PRDX2 BOSS Text Mining PRRT2 BOSS Text Mining PTGS1 BOSS Text Mining PTH BOSS Text Mining RAPGEF5 BOSS Text Mining RHO BOSS Text Mining RNASEH2A BOSS Text Mining RNY4 BOSS Text Mining ROCK1 BOSS Text Mining ROS1 BOSS Text Mining SAA1 BOSS Text Mining SLC10A1 BOSS Text Mining SLC17A5 BOSS Text Mining SLC25A16 BOSS Text Mining SLC25A20 BOSS Text Mining SLC52A2 BOSS Text Mining SLC7A1 BOSS Text Mining SLCO1A2 BOSS Text Mining SLCO2B1 BOSS Text Mining SOD1 BOSS Text Mining SPARC BOSS Text Mining SRL BOSS Text Mining STAT3 BOSS Text Mining TAOK1 BOSS Text Mining TCOF1 BOSS Text Mining TFRC BOSS Text Mining THM BOSS Text Mining TLR4 BOSS Text Mining TMED1 BOSS Text Mining TNF BOSS Text Mining TP53 BOSS Text Mining TRAPPC9 BOSS Text Mining TRIM5 BOSS Text Mining USO1 BOSS Text Mining VCAM1 BOSS Text Mining VEGFA BOSS Text Mining VEGFC BOSS Text Mining VIM BOSS Text Mining VIPR1 BOSS Text Mining WDTC1 BOSS Text Mining WLS BOSS Text Mining WT1
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