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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : Boss - 2,3,7,8-tetrachlorodibenzo-p-dioxin

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Collection	D4 : Boss
Chemical Name	2,3,7,8-tetrachlorodibenzo-p-dioxin ( From PubChem : TETRADIOXIN )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 321.971 g/mol 0 2 6.1982 False(3/4)
Structure
InChI	InChI=1S/C12H4Cl4O2/c13-5-1-9-10(2-6(5)14)18-12-4-8(16)7(15)3-11(12)17-9/h1-4H
InChIKey	HGUFODBRKLSHSI-UHFFFAOYSA-N
Links
Gene (39 / 44) ⊖ Less	Source Type Unit Value Gene PMID Assay Other BOSS Text Mining ACHE BOSS Text Mining AHR BOSS Text Mining ALDH3A1 BOSS Text Mining ATP8A2 BOSS Text Mining AURKB BOSS Text Mining CASP3 BOSS Text Mining CD4 BOSS Text Mining CD86 BOSS Text Mining CDT1 BOSS Text Mining CYGB BOSS Text Mining CYP2B6 BOSS Text Mining CYP2C8 BOSS Text Mining DDR2 BOSS Text Mining ESR1 BOSS Text Mining FOXP3 BOSS Text Mining GPX1 BOSS Text Mining HBB BOSS Text Mining HEBP1 BOSS Text Mining HMOX1 BOSS Text Mining IDO1 BOSS Text Mining IL10 BOSS Text Mining IL27 BOSS Text Mining IL2RA BOSS Text Mining IL4 BOSS Text Mining IL6 BOSS Text Mining INS BOSS Text Mining ITGB2 BOSS Text Mining KRT6B BOSS Text Mining LDHA BOSS Text Mining MAPK3 BOSS Text Mining MIA3 BOSS Text Mining PAH BOSS Text Mining RNASEH2A BOSS Text Mining SLC26A1 BOSS Text Mining SLC52A2 BOSS Text Mining SLC7A1 BOSS Text Mining TNF BOSS Text Mining TP53 PubChem AhR Potency (uM) uM 0.001 AHR - GI(Protien) : PubChem Potency-Replicate_1 uM 0.001 AHR - GI(Protien) : PubChem ER Potency (uM) uM 0.000 ESR1 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.001 ESR1 - GI(Protien) : PubChem Ratio Potency (uM) uM 0.001 NFE2L2 - GI(Protien) : ChEMBL Activity - AHR - Target : CHEMBL3201
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