Tan Lab | DSigDB

Gene Set: D4 : Boss - casein kinase ii inhibitor i

Collection

D4 : Boss

Chemical Name

casein kinase ii inhibitor i ( From PubChem : 4,5,6,7-TETRABROMOBENZOTRIAZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
434.708 g/mol	1	2	4.0079	True

Structure

InChI

InChI=1S/C6HBr4N3/c7-1-2(8)4(10)6-5(3(1)9)11-13-12-6/h(H,11,12,13)

InChIKey

Links

Gene (14 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			AURKB
BOSS	Text Mining			PTEN
PubChem	Potency	uM	25.919	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	28.184	ATXN2	-	GI(Protien) :
PubChem	Potency	uM	2.512	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	3.162	CYP3A4	-	GI(Protien) :
PubChem	None	uM		GEM	-	GI(Protien) :
PubChem	None	uM		ITPKC	-	GI(Protien) :
PubChem	Potency	uM	28.184	KAT2A	-	GI(Protien) :
PubChem	Potency	uM	18.356	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	5.012	NFKB1	-	GI(Protien) :
PubChem	None	uM		PIM1	-	GI(Protien) :
PubChem	None	uM		PIM2	-	GI(Protien) :
PubChem	Potency	uM	56.234	USP1	-	GI(Protien) :
PubChem	Potency	uM	44.668	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	25918.500	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	2511.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	3162.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	28183.800	KAT2A	-	Target : CHEMBL5501
ChEMBL	Potency	nM	18356.400	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	5011.900	NFKB1	-	Target : CHEMBL3251

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