Tan Lab | DSigDB

Gene Set: D4 : Boss - c18h19cln4

Collection

D4 : Boss

Chemical Name

c18h19cln4 ( From PubChem : CLOZAPINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
326.823 g/mol	1	4	1.4793	True

Structure

InChI

InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3

InChIKey

ZUXABONWMNSFBN-UHFFFAOYSA-N

Links

Gene (71 / 102)

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Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			AATF
BOSS	Text Mining			ACHE
BOSS	Text Mining			ACP2
BOSS	Text Mining			ATP8A2
BOSS	Text Mining			BDNF-AS
BOSS	Text Mining			BORA
BOSS	Text Mining			C7orf49
BOSS	Text Mining			CD52
BOSS	Text Mining			CDT1
BOSS	Text Mining			CNR1
BOSS	Text Mining			CSF2
BOSS	Text Mining			CSF3
BOSS	Text Mining			CYGB
BOSS	Text Mining			CYP2B6
BOSS	Text Mining			CYP2C8
BOSS	Text Mining			DDR2
BOSS	Text Mining			DRD3
BOSS	Text Mining			FGA
BOSS	Text Mining			GCG
BOSS	Text Mining			GRIN2B
BOSS	Text Mining			GRM2
BOSS	Text Mining			HTR2A
BOSS	Text Mining			HTR2C
BOSS	Text Mining			HTR4
BOSS	Text Mining			IL6
BOSS	Text Mining			INS
BOSS	Text Mining			LEP
BOSS	Text Mining			LOH19CR1
BOSS	Text Mining			MAPK3
BOSS	Text Mining			NNT
BOSS	Text Mining			NRG1
BOSS	Text Mining			NRXN1
BOSS	Text Mining			OPTN
BOSS	Text Mining			P2RY2
BOSS	Text Mining			PNPLA3
BOSS	Text Mining			PPIG
BOSS	Text Mining			PRCP
BOSS	Text Mining			PRL
BOSS	Text Mining			PTK2B
BOSS	Text Mining			REG3A
BOSS	Text Mining			SLC1A1
BOSS	Text Mining			SLC6A3
BOSS	Text Mining			TACR2
BOSS	Text Mining			TNF
BOSS	Text Mining			TNFRSF13C
PubChem	AR Potency (uM)	uM	28.726	AR	-	GI(Protien) :
PubChem	Potency	uM	79.433	CBX1	-	GI(Protien) :
PubChem	None	uM		CHRM1	-	GI(Protien) :
PubChem	None	uM		CHRM4	-	GI(Protien) :
PubChem	None	uM		CHRM5	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	0.631	DRD1	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1F		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR5A		GI(Protien) :
PubChem	None	uM		HTR5A		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		HTR7		GI(Protien) :
PubChem	None	uM		HTR7		GI(Protien) :
PubChem	None	uM		HTR7		GI(Protien) :
PubChem	None	uM		MAPT	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	Potency	uM	79.433	POLI	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	None	uM		RGS4	-	GI(Protien) :
PubChem	Potency	uM	16.360	TDP1	-	GI(Protien) :
PubChem	Potency	uM	18.837	TDP1	-	GI(Protien) :
PubChem	Potency	uM	23.715	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	79432.800	CBX1	-	Target : CHEMBL1741193
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	631.000	DRD1	-	Target : CHEMBL2056
ChEMBL	Activity	-		DRD2	-	Target : CHEMBL217
ChEMBL	Inhibition	-		HTR7	-	Target : CHEMBL3155

Download gene sets

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