Tan Lab | DSigDB

Gene Set: D4 : Boss - benzotiazida

Collection

D4 : Boss

Chemical Name

benzotiazida ( From PubChem : BENZTHIAZIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
431.937 g/mol	2	8	4.869	True

Structure

InChI

InChI=1S/C15H14ClN3O4S3/c16-11-6-12-14(7-13(11)25(17,20)21)26(22,23)19-15(18-12)9-24-8-10-4-2-1-3-5-10/h1-7H,8-9H2,(H,18,19)(H2,17,20,21)

InChIKey

Links

Gene (25 / 31)

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Source	Type	Unit	Value	Gene	PMID	Other
BOSS	Text Mining			ATN1
BOSS	Text Mining			ATP1B1
BOSS	Text Mining			ATP8A2
BOSS	Text Mining			AURKB
BOSS	Text Mining			BRIP1
BOSS	Text Mining			CEBPZ
BOSS	Text Mining			CFB
BOSS	Text Mining			GPX1
BOSS	Text Mining			HPD
BOSS	Text Mining			KCNJ14
BOSS	Text Mining			NDUFA5
BOSS	Text Mining			OPTN
BOSS	Text Mining			PCBP1
BOSS	Text Mining			PITX1
BOSS	Text Mining			PRDX1
BOSS	Text Mining			PRDX2
BOSS	Text Mining			PTBP2
BOSS	Text Mining			RBPJL
BOSS	Text Mining			SLC43A2
BOSS	Text Mining			SLC7A1
BOSS	Text Mining			TXN
PubChem	None	uM		ABCB1	-	GI(Protien) :
PubChem	Potency	uM	89.125	BAZ2B	-	GI(Protien) :
PubChem	Potency	uM	12.589	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	25.119	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	None	uM		PAFAH2	-	GI(Protien) :
ChEMBL	Potency	nM	89125.100	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	AC50	nM	12589.200	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	12589.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	25118.900	CYP3A4	-	Target : CHEMBL340

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